Best Of: Finding Dora Richardson, The Forgotten Developer of Tamoxifen, a Lifesaving Breast Cancer Therapy - Episode One
In the early 1960s, Dr. Dora Richardson synthesized a chemical compound that became one of the most important drugs to treat breast cancer: tamoxifen. Although her name is on the original patent, her contributions have been lost to history.In the first episode of this two-part podcast, Katie Couric introduces us to Dora’s story, and we show how Lost Women of Science producer Marcy Thompson tracked down Dora’s firsthand account of the history of the drug’s development. This document, lost for decades, tells the story of how the compound was made and how Imperial Chemical Industries, where Richardson worked, almost terminated the project because the company was hoping to produce a contraceptive, not a cancer therapy.This Best Of episode first aired in October 2024 to coincide with Breast Cancer Awareness month. It is now also available in a Spanish adaptation, narrated by Laura Gómez.
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Encontrando a Dora Richardson – Episodio 1
A principios de la década de los sesenta, la Dra. Dora Richardson sintetizó un compuesto químico que se convirtió en uno de los medicamentos más importantes para tratar el cáncer de mama: el tamoxifeno. Aunque su nombre aparece en la patente original, sus contribuciones fueron olvidadas por la historia. En el primer episodio de este podcast de dos partes, les contamos la historia de Dora y de cómo Marcy Thompson, productora de Lost Women of Science, rastreó su relato en primera persona sobre el desarrollo del medicamento. Este documento, perdido durante décadas, narra cómo se creó el compuesto y cómo la empresa Imperial Chemical Industries, donde trabajaba Richardson, estuvo a punto de cancelar el proyecto porque buscaba desarrollar un anticonceptivo, no una terapia contra el cáncer.
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Opening Doors to Computer Science
In high school, Carla Brodley was almost shut out of computer science when boys took over all the computers. But she rediscovered her love for the field in college and has made it her mission to open doors for others. At Northeastern University, she founded the Center for Inclusive Computing, which now partners with more than 100 institutions to make computer science more accessible. As a result of Brodley’s push to introduce more flexible degree programs, more women — and especially more women of color — have not only enrolled but stayed in the field. Now, with support from Pivotal, a group of organizations founded by Melinda French Gates, Brodley is aiming to scale up her efforts. Today she joins Lost Women of Science host Katie Hafner to share her journey, new paths to computer science, and how AI fits in.
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Frances Glessner Lee: The Mother of Forensic Science
Frances Glessner Lee discovered her true calling later in life. An heiress without formal schooling, she was in her fifties when she transformed her fascination with true crime and medicine into the foundation of a new field: forensic science. In the late 1920s, she drew inspiration from a family friend, a medical examiner involved in notorious cases— including the infamous Sacco and Vanzetti trial. For Glessner Lee, the puzzle of untangling the truth about violent deaths proved irresistible. She recognized that solving crimes demanded both rigorous methods and professional training. She funded and helped found the Department of Legal Medicine at Harvard University. Her most unusual teaching tool: intricately crafted dollhouse dioramas depicting grisly crime scenes.
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The Mothers of Gynecology
In this episode, Katie Hafner joins Alexis Pedrick and Mariel Carr to bring you The Mothers of Gynecology, part of Innate: How Science Invented the Myth of Race, a podcast and magazine project produced by the Science History Institute that explores the historical roots and persistent legacies of racism in American science and medicine.Of all wealthy countries, the United States is the most dangerous place to have a baby. The maternal mortality rate is abysmal, and it's getting worse. And there are huge racial disparities: Black women are three times more likely to die in childbirth than white women. Despite some claims to the contrary, the problem isn’t race, it’s racism.This episode, which first aired in April, 2023, explores the racial disparities in maternal health in the US rooted in 19th century medical exploitation of enslaved women.
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For every Marie Curie or Rosalind Franklin whose story has been told, hundreds of female scientists remain unknown to the public at large. In this series, we illuminate the lives and work of a diverse array of groundbreaking scientists who, because of time, place and gender, have gone largely unrecognized. Each season we focus on a different scientist, putting her narrative into context, explaining not just the science but also the social and historical conditions in which she lived and worked. We also bring these stories to the present, painting a full picture of how her work endures.