Tomorrow's Cure

Cardiovascular disease remains the leading cause of death in the United States, yet new science and smarter systems are changing what is possible for patients and families. In this episode of Tomorrow’s Cure, host Cathy Wurzer talks with three leaders who are reshaping how we prevent, understand, and treat heart disease and obesity.

Mayo Clinic gastroenterologist Dr. Andres Acosta explains why obesity is not “one size fits all” and how phenotype based, precision treatments can double weight loss success and reduce cardiovascular risk. American Heart Association CEO Nancy Brown explores why heart disease still claims so many lives, how social and economic forces drive risk, and what it will take to improve health for every community. Dr. Kevin Volpp, scientific lead of the AHA Food is Medicine initiative, shares how medically tailored meals and behavioral economics could cut costly hospital readmissions and make healthy eating more affordable. Listen to hear personal stories, practical takeaways, and a hopeful look at the future of heart health.

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Rheumatoid arthritis is often seen as “just” joint pain, but Mayo Clinic rheumatologist Dr. John Davis and University of Colorado researcher Dr. Kevin Deane reveal a far more complex and promising story. In this episode of Tomorrow’s Cure, host and journalist Cathy Wurzer explores how autoimmune disease can quietly develop for years before the first swollen joint, and how new blood tests, gut microbiome insights, and the exposome, our lifetime of environmental exposures such as cigarette smoke and wildfire haze, are helping clinicians see risk much earlier.

The conversation dives into emerging tools that use artificial intelligence to sift through genetics, autoantibodies, microbiome data, and real-world exposures to predict who is most likely to develop rheumatoid arthritis and who will respond to specific treatments. Hear how prevention trials, lessons from type 1 diabetes, and more virtual models of care could change what it means to live with, or even avoid, rheumatoid arthritis in the future.

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Skin is the body’s largest organ, and its health can reveal far more about aging and disease than what shows up in the mirror. In this episode of Tomorrow’s Cure from Mayo Clinic, host Cathy Wurzer talks with dermatologist and regenerative medicine expert Dr. Saranya Wyles of Mayo Clinic and biomedical engineer Dr. Adam Feinberg of Carnegie Mellon University about “SkinSpan” and the fast-moving world of 3D bioprinted skin.

They explore how layered, living skin models built from human cells and collagen are helping researchers study conditions like eczema, chronic wounds, burns, and age-related changes in skin structure and pigment. The episode also dives into Dr. Feinberg’s hands-on, open-source bioprinting workshops, where clinicians and scientists build their own high-performance bioprinters for a fraction of traditional costs. In turn, democratizing access to advanced regenerative tools and accelerating discovery worldwide. Through these collaborations, bioprinting moves from theory to practice, enabling more teams to test new therapies and customize tissue models for their patients.

The conversation further explores “zombie cells” (senescent cells), what they reveal about skin aging and inflammation, and how skin changes may influence whole-body health. Listeners will also hear about the ethical and practical questions that must be answered before bioprinted skin can reach routine patient care.

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In Season 4 of Tomorrow’s Cure, host Cathy Wurzer interviews physicians, scientists, and medical innovators from Mayo Clinic and other leading institutions to explore breakthroughs in health care, medical research, and patient care. From 3D-printed skin and predictive tools for autoimmune disease to patient-centered AI and lifesaving advancements in organ transplantation, this season brings the future of medicine to the present through real stories and real science.

Across eight in-depth conversations, we’ll discuss the breakthroughs most of us don’t hear about and the ways medicine is becoming smarter, more human, and more connected. Whether you are a patient, clinician, or simply curious about where medicine is headed next, Tomorrow’s Cure offers accessible, thought-provoking insights anywhere you listen to your podcasts. 

How to listen and stay connected:

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This week’s episode of Tomorrow’s Cure takes you inside the PlatforMed Conference 2025. With over 250 global leaders from healthcare, government, academia, and business, the event explored how platform thinking is transforming the future of clinical care. 
Get the latest health information from Mayo Clinic's experts, subscribe to Mayo Clinic’s newsletter for free today:  https://mayocl.in/3EcNPNc