Rings a Bell

The one, the only, Dr. Shelita Dattani quizzes Kim on the 2025 Hypertension Canada guidelines.

Dr. Shelita Dattani is a nationally and internationally recognized pharmacy leader, advocate, and speaker with over 25 years of experience across community practice, hospital settings, academia, industry and national associations. Shelitta is on the board of Hypertension Canada and knows the 2025 Hypertension Canada guidelines inside and out.

The full guidelines are available at hypertension.ca

If you want to see references from this episode, follow the show on socials, sign up for the email list, donate via "buy me a coffee" or send me an email you can do so using this link: https://ringsabellpod.kit.com/allthethings

Shelita can be found on LinkedIn here: https://www.linkedin.com/in/shelita-dattani-pharmd-a117aa1a/ or on instagram @shelsrx.
You can also email Shelita at [email protected].

Here are the chapters for this episode:
00:00 - Introduction
04:00 - How big is the hypertension problem in Canada?
10:33 - How does Canada compare to the rest of the globe in terms of hypertension prevalence and management?
15:30 - The case for pharmacist management of uncomplicated hypertension.
19:14 - What is the recommended technique for measuring blood pressure according to the 2025 hypertension Canada guidelines?
22:37 - What proportion of people have white coat hypertension?
23:56 - What is masked hypertension?
24:13 - What is the gold standard for checking blood pressure?
25:52 - Why do we need to keep our feet flat on the floor when checking blood pressure? (and other tips for accurate blood pressure readings).
32:09 - The problem with blood pressure kiosks in pharmacies and the case for a counselling room pharmacist directed blood pressure measurement.
38:11 - What is the target blood pressure for everyone now?
41:54 - What is the number needed to harm for treating hypertension to 130/80 mmHg?
45:23 - What makes a person high cardiovascular risk and how do we treat their hypertension vs. someone with low cardiovascular risk?
48:36 - What are the recommendations for lifestyle interventions according to the 2025 Hypertension Canada Guidelines?
50:42 - Where do we get most of the sodium in our modern diets?
52:37 - What is the impact of alcohol on blood pressure?
56:51 - What is the pharmacotherapy strategy for treating hypertension according to the 2025 Hypertension Canada Guidelines?
1:03:00 - Do Angiotensin Receptor Blockers cause coughs?
1:04:00 - Can you use an ACE and an ARB together?
1:08:00 - Do we use beta blockers to control uncomplicated hypertension?
1:13:36 - Wrap up

Hosted on Acast. See acast.com/privacy for more information.

Are you anxious about what you don’t remember about anxiety therapy? Well have I got a treat for you. Episode 6 of Rings A Bell Podcast! Rami Safi, a pharmacist and psychotherapist (qualifying) brings us the good bad and the ugly of anxiety management. Enjoy a comprehensive overview of pathophysiology, pharmacology and therapeutics with a few helpful tips for managing your own anxiety along the way!

Topics Covered
00:00 - Introduction and housekeeping
00:44 - Rami’s journey from pharmacist to pharmacist and psychotherapist
07:22 - Pervasiveness and importance of anxiety
08:45 - Connection between perfectionism and anxiety
11:30 - Neurotransmitters involved in anxiety disorders
13:22 - Neurobiological difference between panic attack and generalized anxiety disorder
19:25 - Role of the amygdala in fear and anxiety
21:50 - First line treatments for generalized anxiety disorder
26:36 - Rapid nervous system regulation techniques
34:07 - St. John’s Wort risks in anxiety disorders
35:38 - Appropriate times to use benzodiazepines in anxiety treatment
36:11 - Managing side effects of selective serotonin reuptake inhibitors
37:45 - Importance of deprescribing benzodiazepines in elderly people
39:29 - Benzodiazepine pharmacokinetics (volume of distribution) (rate of clearance) (implications in obesity and elderly)
42:25 - Preferred benzodiazepines in elderly people
43:02 - Mechanism of action of buspirone
44:25 - Meds used in psychology with narrow therapeutic window
45:52 - Lithium and kidney function
47:49 - Serious drug interactions with SSRIs
48:45 - Intersection of chronic pain, depression and insomnia
50:35 - moral model of substance use vs. biopsychosocial model of substance use
56:34 - wrap up

Connect with Rami Safi
LinkedIn: https://www.linkedin.com/in/rami-s-98186718/
Wellness Wave Pharmacy in Hamilton: https://wellnesswavepharmacy.ca/

All the Links!
Find all the links to all the things (references, resources, buy me a coffee, email list, etc) here: https://ringsabellpod.kit.com/allthethings

#anxiety #pathophysiology #pharmacology #anxietytherapeutics #therapeutics #continuingeducation#continuingeducation #pharmacy #pharmacylife #pharmacylyfe #pharmacistlife #pharmacistlyfe #itsmyanxiety #weallhaveanxiety #anxietymanagement #ssris #snris #serotonin #dopamine #norepinephrine #panicattacks #bzds #benzos #obesitymedicine #geriatricmedicine #benzodiazepines #diazepam #pharmacokinetics #volumeofdistribution #eliminationhalflife #neurology #psychotherapy #cbt #cognitivebehaviouraltherapy #GAD #generalizedanxietydisorder #SJW #stjohnswort #substanceuse
Hosted on Acast. See acast.com/privacy for more information.

Episode 5 - Antibiotic Stewardship with Brad Phillips

Episode 5 provides:
A refresher on bacteriostatic vs. bactericidal antibiotics
The ACTUAL rates of true penicillin allergy
Why “walking pneumonia” is more of a slang term than a diagnosis
The declining efficacy of azithromycin
Where to find up to date resistance patterns
Some oral options for uncomplicated MRSA
Adapting prescriptions with confidence
and much more!

Thinkwear Collective!

You can purchase Thinkwear at https://lindsay-dixon-shop.fourthwall.com/en-cad

Enter the giveaway by interacting with the show in the following ways:
comment or share any of the social media posts about Episode 5
leave a review on any of the podcast platforms
Send me your honest thoughts about the show and what I can do to improve it ([email protected])
Spread the show through word of mouth to a colleague or a friend and then let me know so I can add you to the draw

All the Links!
Find all the links to all the things (references, resources, buy me a coffee, email list, etc) here: https://ringsabellpod.kit.com/allthethings
Hosted on Acast. See acast.com/privacy for more information.

Episode 4 provides
- A refresher on how red blood cells are formed, their lifecycle and inputs
- An overview of the major types of anemia classified by pathophysiology and histology (how the red blood cells look under a slide)
- Some simple physical symptoms that pharmacists can look for in practice and what they might indicate
- A refresher on the major guidelines for iron deficiency anemia including a recent update
- Some excellent case studies detailing the complexity of dealing with patients who have chronic inflammation AND anemia
- New this episode: some semi-useful notes in pdf form from me to you. Merry Christmas ya bunch of hooligans!

Links:
Find all the links to all the things here: https://ringsabellpod.kit.com/allthethings

Find Jenny at: https://www.linkedin.com/in/jenny-hsieh-435828177/

References:
See all the links above.
Hosted on Acast. See acast.com/privacy for more information.

Keywords:
insulin sensitivity, metformin, blood sugar management, dietary approaches, microbiome, GLP-1 agonists, functional medicine, probiotics, metabolic health, clinical signs

Summary:
Episode 3 part 1 covers general metabolic health as it relates to pharmaceuticals, the microbiome and nutrition. My guest is Dr. Alex Nataros, a family doctor practicing in Port Hardy, BC.

Subscribe to the Rings a Bell email list here: https://ringsabellpod.kit.com/subscribe

To become a guest on the show email [email protected]

References:
Weight Gain Drugs
https://pmc.ncbi.nlm.nih.gov/articles/PMC6109660/
Weight loss drugs
https://mobile.fpnotebook.com/Endo/Pharm/MdctnsAsctdWthUntntnlWghtLs.htm
Insulin Sensitivity Drugs
Giglio RV, Papanas N, Rizvi AA, Ciaccio M, Patti AM, Ilias I, Pantea Stoian A, Sahebkar A, Janez A, Rizzo M. An Update on the Current and Emerging Use of Thiazolidinediones for Type 2 Diabetes. Medicina. 2022; 58(10):1475. https://doi.org/10.3390/medicina58101475
Laurindo LF, Barbalho SM, Guiguer EL, da Silva Soares de Souza M, de Souza GA, Fidalgo TM, Araújo AC, de Souza Gonzaga HF, de Bortoli Teixeira D, de Oliveira Silva Ullmann T, et al. GLP-1a: Going beyond Traditional Use. International Journal of Molecular Sciences. 2022; 23(2):739. https://doi.org/10.3390/ijms23020739
https://doi.org/10.1016/j.redox.2020.101517 (Mechanisms of Action of metformin in type 2 diabetes: effects on mitochondria and leukocyte endothelium interactions.
Microbiome and obesity:
https://doi.org/10.1016/j.biopha.2022.112678
Sohail MU, Althani A, Anwar H, Rizzi R, Marei HE. Role of the Gastrointestinal Tract Microbiome in the Pathophysiology of Diabetes Mellitus. J Diabetes Res. 2017;2017:9631435. doi:10.1155/2017/9631435
HMF Metabolic:
Michael DR, Jack AA, Masetti G, et al. A randomised controlled study shows supplementation of overweight and obese adults with lactobacilli and bifidobacteria reduces bodyweight and improves well-being. Sci Rep. 2020;10(1):4183. Published 2020 Mar 6. doi:10.1038/s41598-020-60991-7
UltraFlora Control:
Stenman LK, Lehtinen MJ, Meland N, et al. Probiotic With or Without Fiber Controls Body Fat Mass, Associated With Serum Zonulin, in Overweight and Obese Adults-Randomized Controlled Trial. EBioMedicine. 2016;13:190-200. doi:10.1016/j.ebiom.2016.10.036
Super intense study on personalized nutrition published in cell that I talked too long about :)
Zeevi D, Korem T, Zmora N, et al. Personalized Nutrition by Prediction of Glycemic Responses. Cell. 2015;163(5):1079-1094. doi:10.1016/j.cell.2015.11.001









Hosted on Acast. See acast.com/privacy for more information.