1492 episodes
20VC: The Best AI Companies Have Unique Data Acquisition Strategies | Will Simile Kill Kalshi, Polymarkets and NASDAQ | How to Sign Fortune 500 Companies As Customers in Weeks with Joon Sung Park, Simile
2026-08-01 | 1h 3 mins.Joon Sung Park is the Founder and CEO of Simile, the AI simulation company building foundation models of human behaviour; allowing companies to test how real people may think, decide and act before making a decision in the real world. Simile has now raised $300 million in total, including a $200 million Series B announced last week at a $2 billion valuation, led by Greenoaks and Index Ventures.
AGENDA:
00:00 We Will Pay $100M for a Single Query on Some Models
10:00 Why Stock Markets May Not Exist in 5 Years Time
15:00 The Best Companies All Have Unique Data Acquisition Strategies
19:00 The Best AI Companies Have Clear and Fast Reward Functions
24:00 How We Sign Fortune 500 Companies for $10M Contracts in Weeks
32:00 Does Similie Kill Kalshi and Polymarket? Prediction vs Changing the Future
42:00 Inside Similie's $300M Raise; What Every Founder Needs to Know20VC: Jensen's Open-Weights Letter | Travis Kalanick Raises $1.7B for Atoms | Google Cloud Grows 82% But The Market Tanks | Francisco Partners Raises $21BN | Etched Raises $300M to Take on Nvidia
2026-07-30 | 1h 17 mins.AGENDA:
05:00 Jensen's Open-Weights Letter Puts Anthropic on an Island 10:00 OpenAI's Model Targets Hugging Face in a Cyber-Security Scare 18:00 America's Open-Model Push Accelerates as China Looms Large 30:00 Etched Raises $300M to Take on Nvidia 34:00 Google Cloud Grows 82%—So Why Did the Market Panic? 41:00 Travis Kalanick Raises $1.7B for Atoms and Physical AI 51:00 Francisco Partners Raises $21B: Can Private Equity Still Save SaaS? 1:00:00 Mark Pincus Says Quit When It's Too Hard—Jason Lemkin Erupts 1:07:00 Stripe vs Revolut: Which $100B+ Fintech Would You Own?20VC: Leading Anthropic's First Ever Round | Will Open Source Threaten Anthropic's Business | Do Margins Matter in a World of AI | Why Triple, Triple, Double, Double is Not Good Enough Today | Why Series A is Hard Today with Matt Murphy @ Menlo
2026-07-27 | 1h 2 mins.Matt Murphy is a Partner at Menlo Ventures, who just raised $3 billion in fresh capital, its largest pool ever. Matt's portfolio includes Anthropic, Lovable, Legora, OpenRouter, Chai Discovery, Axiom, OpenEvidence and more.
AGENDA:
00:00 Why Menlo Broke All Its Investing Rules to Back Anthropic 09:00 Why Ownership Matters Less in an Outlier-Driven Venture Market 13:00 Do We Have an SPV Problem in Venture Today? 20:00 Do Margins Still Matter in AI? 23:00 Why Open Source Won't Derail Anthropic's Growth 26:00 Does Every Model Provider Need to Build Its Own Chips? 29:00 Why Anthropic Is Not a Threat to Legora 32:00 Why Series A Is the Hardest Place to Invest Today 36:00 Why Signalling Is B.S. and Every Fund Is Going Full Stack 42:00 Why Building a Company in Europe Is Hard Mode 47:00 Why Triple-Triple-Double-Double Is No Longer Venture-Scale Growth20VC: Mercor CPO on Revenue Concentration from Frontier Labs | Why Large Enterprise is Scared to Partner with Frontier Labs | Why Small Specialised Models is the Future with Osvald Nitski
2026-07-25 | 1hOsvald Nitski is the Chief Product Officer at Mercor, the AI-training and expert-data marketplace powering frontier-model development. Mercor last raised a $350 million Series C at a $10 billion valuation, and is reportedly in discussions for a new round at a $20 billion valuation. Mercor crossed $2BN in ARR in June; doubling from $1 billion in only four months.
AGENDA:
00:04:00 Will open-source models kill the data-provider business?
00:07:00 Are enterprises still terrified of working with frontier model companies?
00:09:00 Does every company end up with its own specialised AI model?
00:10:00 Do enterprises actually have an AI ROI problem?
00:11:00 How should founders balance AI performance against exploding token bills?
00:14:00 Does AI mean product teams build 10x more—or ruthlessly simplify?
00:15:00 What does it now take to be a great product manager in an AI-native world?
00:20:00 Is the boom in AI services and forward-deployed engineers here to stay?
00:37:00 Can Mercor escape its dependence on a handful of frontier-model customers?
00:47:00 Are AI-generated code and agents creating a cybersecurity arms race?
00:56:00 When will robotics have its real "ChatGPT moment"?20VC: OpenAI and Anthropic Threatened by Kimi? | Should the US Ban Chinese Open-Source Models | Should Openrouter Sell & Value in the Routing Layer? | Stripe Buying Paypal: What You Need to Know
2026-07-23 | 1h 23 mins.AGENDA:
00:04 China's Kimi and Qwen Put Frontier AI on Notice00:08 Washington Debates Whether Chinese AI Models Should Be Banned 00:17 Can America Build a Profitable Open-Weight AI Champion? 00:21 OpenRouter's Moment: Is This the Perfect Time to Sell? 00:31 Fireworks' $1.5B Raise Signals the Real AI Money Is in Infrastructure 00:39 Why Every Great AI App May Need to Build Its Own Model 00:50 Stripe's Bold Play to Buy PayPal 01:01 The AI Funding Frenzy: Why Late-Stage Venture Is Winning 01:12 Nuclear Startups Go Wild While Databricks and Stripe Stay Private 01:15 The AI Supply Chain War: TSMC, ASML, DRAM—and Nvidia's Next Move
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