The Dr. Josh Axe Show

Dr. Gez Agolli has spent nearly 30 years using integrative medicine to treat cancer, autoimmune disease, and chronic illness — and what he's found challenges almost everything conventional medicine teaches about healing. Josh calls him one of his top two mentors in functional medicine, and this conversation covers the full protocol: terrain, toxicity, advanced therapies, and why testing matters more than guessing.

In This Episode:
- Why toxicity — not just genetics — is the #1 root cause of cancer right now, and what 3.3 billion pounds of environmental chemicals are doing to the body's terrain
- How hyperthermia, high-dose vitamin C (the right kind), and hyperbaric oxygen work together — and which chemotherapy drugs make hyperbaric oxygen contraindicated
- What insulin potentiation therapy (IPT) actually does: using fractionated chemo alongside glucose to target cancer cells directly
- The circulating tumor cell tests and liquid biopsy markers (including Signatera and ctDNA) that can predict cancer recurrence 6–12 months before a scan shows anything
- Why leaky gut is the root cause of autoimmune disease — and what Dr. Agolli's testing protocol reveals that most doctors never order
- The glutathione, F2-isoprostane, and GGT markers that measure oxidative stress at the cellular level, and what happens when you address them

Chapters:
- "00:00:00" – Intro: Cancer Stats & Meeting Dr. Guez Agolli
- "00:02:47" – His Origin Story & the Broken Healthcare System
- "00:06:50" – What Cancer Is: Cell Biology & Root Causes
- "00:13:46" – Sponsor Break: Heal Yourself Book
- "00:14:31" – Parasites, Immune System & Terrain Theory
- "00:19:57" – Advanced Cancer Testing: The RGCC (Greek) Test
- "00:25:38" – Top Cancer Therapies: Hyperthermia, IPT & the 40-Day Protocol
- "00:39:26" – Sponsor Break: Health Institute Bloodwork
- "00:40:27" – Testing Philosophy: Micronutrients, Food Sensitivities & Glucose
- "00:54:44" – Glutathione, Longevity & Reversing Autoimmune Disease
- "01:05:12" – Mitochondria, Closing Thoughts & Closing

Uncover what’s really going on in your body with advanced biomarker testing for hormones, thyroid, and metabolism— plus a 1-hour consultation with a Senior Health Advisor! → http://mybloodwork.com

*Disclaimer: The bloodwork our team runs at mybloodwork.com covers a handful of the biomarkers listed in the guide above — including critical thyroid and metabolic markers — plus a 1-hour consultation with a Senior Health Advisor, but does NOT cover all 25. You will want to consult your primary or functional doctor for the entire list.

Thank you to our sponsors!

Sunlighten Sauna: https://get.sunlighten.com/axepodcast

Manukora Manuka Honey: https://manukora.com/axe

Watch The Dr. Josh Axe Show every Monday & Thursday on YouTube: / @drjoshaxe

🎧 Early Access! Our listeners enjoy every episode before anyone else!

Tune in below and join our exclusive group of listeners → Spotify: https://bit.ly/DrJoshAxeSpotify
Apple Podcast: https://apple.co/3JDvWcS

Order my NEW BOOK, Heal Your Cells → www.healyourcellsbook.com

Watch my free training on how to naturally balance your blood sugar and reverse your symptoms → http://DrAxeDiabetesClass.com
Discover practical steps you can take today to start healing your thyroid naturally → http://DrAxeThyroidClass.com
If you’re ready to start feeling like yourself again and balance your hormones, take my free class → http://DrAxeHormoneClass.com

CONNECT WITH DR. JOSH AXE
Instagram → / drjoshaxe
Facebook → / drjoshaxe
TikTok → / thedrjoshaxeshow
X → https://x.com/drjoshaxe/
LinkedIn → / joshaxe
Website → http://thehealthinstitute.com
Sign up for my newsletter → https://bit.ly/4oE9Jf3
Ask Dr. Axe → http://speakpipe.com/drjoshaxe

CONNECT WITH OUR GUEST
Instagram → @progressivemedicalcenter
TikTok → @progressivemedicalctr
LinkedIn → Gez Agolli
YouTube → Progressive Medical Center / Rethink My Health Website → Progressive Medical Center

DISCLAIMER
This content is strictly the opinion of Dr. Josh Axe and is for informational and educational purposes only. It is not intended to provide medical advice or to take the place of medical advice or treatment from a personal physician. All viewers of this content are advised to consult their doctors or qualified health professionals regarding specific health questions. Neither Dr. Axe nor the publisher of this content takes responsibility for possible health consequences of any person or persons reading or following the information in this educational content. All viewers of this content, especially those taking prescription or over-the-counter medications, should consult their physicians before beginning any nutrition, supplement or lifestyle program.

Your hormones, your sleep, your stress, your diet — they may all be affecting your health at a much deeper level than you realize. Dr. Josh Axe sits down with functional medicine expert Dr. Will Cole and fitness and biohacking educator Dylan Gemelli for a no-holds-barred roundtable on what may actually be driving chronic disease, accelerated aging, hormonal dysfunction, and poor metabolic health — and why healing may need to start at the cellular level. In this episode, we learn why Dr. Axe and Dr. Cole believe cellular health could change how we approach chronic disease — and how to identify which systems in your body may be aging faster than others.

Uncover what’s really going on in your body with advanced biomarker testing for hormones, thyroid, and metabolism — plus a 1-hour consultation with a Senior Health Advisor! → http://mybloodwork.com

Disclaimer: The bloodwork our team runs at mybloodwork.com covers a handful of the biomarkers listed in the guide above — including critical thyroid and metabolic markers — plus a 1-hour consultation with a Senior Health Advisor, but does NOT cover all 25. You will want to consult your primary or functional doctor for the entire list.

 

Thank you to our sponsors!

Sunlighten Sauna → https://get.sunlighten.com/axepodcast

Manukora Manuka Honey → https://manukora.com/axe

Watch The Dr. Josh Axe Show every Monday & Thursday on YouTube → https://www.youtube.com/@drjoshaxe?sub_confirmation=1

🎧 **Early Access!**

Our listeners enjoy every episode before anyone else!

Tune in below and join our exclusive group of listeners → Spotify → https://bit.ly/DrJoshAxeSpotify

Apple Podcasts → https://apple.co/3JDvWcS

Order our NEW BOOK, *Heal Your Cells* → healyourcellsbook.com

Watch my free training on how to naturally balance your blood sugar and reverse your symptoms → http://DrAxeDiabetesClass.com

Discover practical steps you can take today to start healing your thyroid naturally → http://DrAxeThyroidClass.com

If you’re ready to start feeling like yourself again and balance your hormones, take my free class → http://DrAxeHormoneClass.com

CONNECT WITH DR. JOSH AXE

Instagram → https://www.instagram.com/drjoshaxe/

Facebook → https://www.facebook.com/DrJoshAxe/

TikTok → https://www.tiktok.com/@thedrjoshaxeshow/

X → https://x.com/drjoshaxe/

LinkedIn → https://www.linkedin.com/in/joshaxe

Website → http://thehealthinstitute.com

Sign up for my newsletter → https://bit.ly/4oE9Jf3

Ask Dr. Axe → http://speakpipe.com/drjoshaxe

CONNECT WITH DR. WILL COLE

Website → https://drwillcole.com

Instagram → https://www.instagram.com/drwillcole/

Podcast → The Art of Being Well

CONNECT WITH DYLAN GEMELLI

Website → https://dylangemelli.com

Instagram → https://www.instagram.com/dylangemelli/

YouTube → https://www.youtube.com/@DylanGemelliBiohacking

Podcast → The Dylan Gemelli Podcast

TIMESTAMPS:

00:00 — The Biggest Drivers of Chronic Disease

02:29 — Welcome to the Health & Longevity Roundtable

03:07 — Why Cellular Health May Be the Future of Medicine

06:10 — Is One of Your Organs Aging Faster Than the Rest?

08:22 — How Early Do Health Problems Really Begin?

12:30 — The Blood Markers That Could Reveal Heart Disease Risk

18:12 — What Insulin Resistance Actually Means

19:59 — The 2 Hormones That Can Throw Everything Off

22:58 — The Surprising Connection Between Sleep & Insulin Resistance 25:10 — “I’ll Sleep When I’m Dead” Is Destroying Your Health

31:32 — Waking Up at 3 A.M.? Cortisol May Be the Reason

32:43 — How to Lower Stress & Support Your Vagus Nerve

37:18 — How Your Mind & Nervous System Affect Your Health

41:32 — Can Childhood Trauma Keep You From Healing?

43:55 — Forgiveness, Faith & the Nervous System

48:11 — Why Dylan Believes Health Starts With “Mind, Body & God”

51:11 — Can Faith Actually Help You Live Longer?

58:35 — The Truth About Peptides & Where Medicine Is Headed

1:03:29 — Are Peptides Overhyped or the Future of Health?

1:05:31 — Conventional vs. Functional Medicine

1:10:14 — How to Increase Your Healthspan, Not Just Your Lifespan

1:11:01 — Why Gut Health Matters for Longevity

1:12:46 — The Best Exercise for Mitochondria & Healthy Aging

1:16:23 — Why Women Shouldn't Be Afraid of Strength Training

1:19:32 — Keto, Carnivore & Vegan: Why Extreme Diets Can Backfire

1:21:29 — Bio-Individuality: There Is No Perfect Diet for Everyone

1:27:30 — Is Health Advice Actually Making People More Stressed?

1:29:03 — Seed Oils vs. Saturated Fat: What's Actually Healthier?

1:39:12 — The 5 Foods Josh Axe & Will Cole Would Choose for Life

1:43:11 — Josh & Will Reveal Their Favorite Cheat Foods

1:45:29 — Are We Eating Too Much Protein?

1:50:01 — Do You Really Need Fiber?

1:55:12 — The #1 Health Lesson From Josh, Will & Dylan

1:57:16 — Dylan's Final Message: God First, Health Second

After 40, your biology rewrites the rules — and most people are still playing the old game. In this episode, Dr. Josh Axe breaks down the 7 mistakes that accelerate aging, why the scale is an outdated marker, and what a study of 140,000 people across 17 countries says actually predicts how long you'll live.

 

In this episode:

- Why muscle loss after 40 is silent, slow, and almost always preventable — and the two-day-a-week fix that reverses it

- The grip strength finding from 140,000 adults that predicts mortality better than blood pressure or cholesterol

- Why GLP-1s and aggressive dieting without strength training leave you metabolically weaker, not stronger

- The blood markers most doctors skip — fasting insulin, ApoB, and high-sensitivity CRP — and why "normal" isn't the same as optimal

- How poor sleep and social isolation are quietly compounding every other health mistake you're making

- Josh's personal protocol after recovering from a spinal infection at 41 — and what his 76-year-old water-skiing father proves is possible

 

Grab our free guide for the Bloodwork Markers that Matter Most: https://bit.ly/draxe25bloodworkmarkers

 

Uncover what’s really going on in your body with advanced biomarker testing for hormones, thyroid, and metabolism— plus a 1-hour consultation with a Senior Health Advisor! →  http://mybloodwork.com

 

*Disclaimer: The bloodwork our team runs at mybloodwork.com covers a handful of the biomarkers listed in the guide above — including critical thyroid and metabolic markers — plus a 1-hour consultation with a Senior Health Advisor, but does NOT cover all 25. You will want to consult your primary or functional doctor for the entire list.

 

Thank you to our sponsors!

Sunlighten Sauna: https://get.sunlighten.com/axepodcast

Manukora Manuka Honey: https://manukora.com/axe

 

Watch The Dr. Josh Axe Show every Monday & Thursday on YouTube: https://www.youtube.com/@drjoshaxe?sub_confirmation=1

 

🎧 Early Access!

Our listeners enjoy every episode before anyone else! Tune in below and join our exclusive group of listeners →

Spotify: https://bit.ly/DrJoshAxeSpotify

Apple Podcast: https://apple.co/3JDvWcS

 

Pre-order my NEW BOOK, Heal Your Cells → healyourcellsbook.com

 

Watch my free training on how to naturally balance your blood sugar and reverse your symptoms → http://DrAxeDiabetesClass.com

 

Discover practical steps you can take today to start healing your thyroid naturally →   http://DrAxeThyroidClass.com

 

If you’re ready to start feeling like yourself again and balance your hormones, take my free class → http://DrAxeHormoneClass.com

 

CONNECT WITH DR. JOSH AXE

Instagram → https://www.instagram.com/drjoshaxe/

Facebook → https://www.facebook.com/DrJoshAxe/

TikTok → https://www.tiktok.com/@thedrjoshaxeshow/

X → https://x.com/drjoshaxe/

LinkedIn → https://www.linkedin.com/in/joshaxe

Website →  http://thehealthinstitute.com

Sign up for my newsletter → https://bit.ly/4oE9Jf3

Ask Dr. Axe → http://speakpipe.com/drjoshaxe 

 

0:00 Introduction

1:28 What changes in your body after 40

5:35 Josh's recovery story and what it taught him

5:41 The grip strength study (140,000 people, 17 countries)

12:43 Mistake #1 — All cardio, no strength training

17:13 Mistake #3 — Poor sleep and light exposure

21:23 Mistake #4 — Not measuring real fitness

23:53 Mistake #5 — Chasing the scale instead of muscle

25:59 Mistake #6 — Flying blind on your blood work

25:59 Mistake #7 — Missing community and social connection

37:22 The fixes: compound lifts, protein anchoring, and sleep

41:11 Home tests to check your fitness this week

 

DISCLAIMER

This content is strictly the opinion of Dr. Josh Axe and is for informational and educational purposes only. It is not intended to provide medical advice or to take the place of medical advice or treatment from a personal physician. All viewers of this content are advised to consult their doctors or qualified health professionals regarding specific health questions. Neither Dr. Axe nor the publisher of this content takes responsibility for possible health consequences of any person or persons reading or following the information in this educational content. All viewers of this content, especially those taking prescription or over-the-counter medications, should consult their physicians before beginning any nutrition, supplement or lifestyle program.

 

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Your clothes, your mattress, your cleaning products — they're all off-gassing chemicals into your body 24 hours a day, and most people have no idea. Alex Clark has spent the last year on the front lines of the MAHA movement, testifying at the White House on glyphosate, exposing what's hiding in cotton tampons, and building one of the most-followed health podcasts in the country — and today she's bringing all of it to this show.

 

**In this episode:**

- Alex's viral $60 morning smoothie — every ingredient, the science behind each one, and whether it's actually setting her up for a blood sugar crash

- Why glyphosate is lurking in places most people never consider: tampons, clothing, and baby products — and what $16 billion in Bayer settlements tell you about the "safe" science

- The problem with polyester blankets, synthetic socks, and fast-fashion baby clothes — and why your skin absorbs what sits on it the same way your gut does

- What really happened when Alex and her coalition were invited to a White House roundtable to confront the current administration's handling of glyphosate policy

- The truth about freshly milled flour, sourdough, and why the last two weeks of ripening are when most of a food's nutrition actually develops

- How to clean your air, replace your bedding, and swap your cleaning products — practical first steps that cost less than you think

 

Uncover what’s really going on in your body with advanced biomarker testing for hormones, thyroid, and metabolism— plus a 1-hour consultation with a Senior Health Advisor! →  http://mybloodwork.com

 

*Disclaimer: The bloodwork our team runs at mybloodwork.com covers a handful of the biomarkers listed in the guide above — including critical thyroid and metabolic markers — plus a 1-hour consultation with a Senior Health Advisor, but does NOT cover all 25. You will want to consult your primary or functional doctor for the entire list.

 

Thank you to our sponsors!

Sunlighten Sauna: https://get.sunlighten.com/axepodcast

Manukora Manuka Honey: https://manukora.com/axe

 

Watch The Dr. Josh Axe Show every Monday & Thursday on YouTube: https://www.youtube.com/@drjoshaxe?sub_confirmation=1

 

🎧 Early Access!

Our listeners enjoy every episode before anyone else! Tune in below and join our exclusive group of listeners →

Spotify: https://bit.ly/DrJoshAxeSpotify

Apple Podcast: https://apple.co/3JDvWcS

 

Pre-order my NEW BOOK, Heal Your Cells → healyourcellsbook.com

 

Watch my free training on how to naturally balance your blood sugar and reverse your symptoms → http://DrAxeDiabetesClass.com

 

Discover practical steps you can take today to start healing your thyroid naturally →   http://DrAxeThyroidClass.com

 

If you’re ready to start feeling like yourself again and balance your hormones, take my free class → http://DrAxeHormoneClass.com

 

CONNECT WITH DR. JOSH AXE

Instagram → https://www.instagram.com/drjoshaxe/

Facebook → https://www.facebook.com/DrJoshAxe/

TikTok → https://www.tiktok.com/@thedrjoshaxeshow/

X → https://x.com/drjoshaxe/

LinkedIn → https://www.linkedin.com/in/joshaxe

Website →  http://thehealthinstitute.com

Sign up for my newsletter → https://bit.ly/4oE9Jf3

Ask Dr. Axe → http://speakpipe.com/drjoshaxe 

 

CONNECT WITH GUEST

Instagram → https://www.instagram.com/realalexclark

Facebook → https://www.facebook.com/realalexclark

TikTok → https://www.tiktok.com/@cultureapothecary

X → https://x.com/Realalexclark

YouTube → https://www.youtube.com/@RealAlexClark

 

0:00 The $60 Smoothie That Made Fox News

3:10 Every Ingredient — and Why

6:13 Blood Sugar, Protein Timing & CGM Testing

8:04 Glyphosate: Where It's Actually Hiding

9:04 The Pesticide Liability Shield Nobody Is Talking About

13:24 The White House Roundtable

16:02 The Monsanto Supreme Court Case & Rescinded Science

19:48 Tampons, Clothing & Baby Products Saturated with Chemicals

22:28 Why Wool and Cotton Beat Every Synthetic Fabric

24:19 Sourdough, Freshly Milled Flour & Nutrient Bioavailability

27:11 Nicotine Patches: The Controversial Episode

32:09 Cradle Cap, Kids' Gut Health & Early Nutrition

43:33 Natural Bedding, Air Purifiers & the Mattress Problem

47:53 Branch Basics, Off-Gassing Cleaning Products & Childhood Eczema

 

DISCLAIMER

This content is strictly the opinion of Dr. Josh Axe and is for informational and educational purposes only. It is not intended to provide medical advice or to take the place of medical advice or treatment from a personal physician. All viewers of this content are advised to consult their doctors or qualified health professionals regarding specific health questions. Neither Dr. Axe nor the publisher of this content takes responsibility for possible health consequences of any person or persons reading or following the information in this educational content. All viewers of this content, especially those taking prescription or over-the-counter medications, should consult their physicians before beginning any nutrition, supplement or lifestyle program.

 

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1 in 6 couples worldwide is now struggling to conceive — and in most cases, the real root causes never get tested. Dr. Josh Axe walks through the 6 functional and ancient medicine root causes driving the infertility epidemic, the suppressed Fauci texts on COVID vaccines and miscarriage risk, and the exact diet, supplement, and lifestyle plan that can shift your fertility in as little as 90 days. Food is medicine, and your body was designed to heal — this episode shows you how to work with it, not against it.

 

**In this episode:**

- The Fauci texts that went public: what he privately said about mRNA vaccines and miscarriage risk, and what two large-scale studies (200,000+ pregnancies) actually found

- The #1 root cause Josh sees in clinical practice — and why fixing blood sugar alone has helped more women conceive than almost anything else

- Why your TSH can look completely normal while thyroid antibodies are silently blocking ovulation and raising miscarriage risk

- The 10-marker fertility blood panel Josh runs — the specific labs (free T3, ferritin, TPO antibodies, fasting insulin) that standard workups miss

- What Chinese medicine calls "kidney yang deficiency" and "damp phlegm," what those patterns actually mean in functional terms, and the warming foods that address both

- The 90-day fertility window: why eggs take 90 days and sperm 74 to mature, and how today's changes show up in 3 months

 

Download my FREE PDF "Fertility Foundations": https://bit.ly/draxefertilityfoundations

 

Uncover what’s really going on in your body with advanced biomarker testing for hormones, thyroid, and metabolism— plus a 1-hour consultation with a Senior Health Advisor! →  http://mybloodwork.com

 

*Disclaimer: The bloodwork our team runs at mybloodwork.com covers a handful of the biomarkers listed in the guide above — including critical thyroid and metabolic markers — plus a 1-hour consultation with a Senior Health Advisor, but does NOT cover all 25. You will want to consult your primary or functional doctor for the entire list.

 

Thank you to our sponsors!

Sunlighten Sauna: https://get.sunlighten.com/axepodcast

Manukora Manuka Honey: https://manukora.com/axe

 

Watch The Dr. Josh Axe Show every Monday & Thursday on YouTube: https://www.youtube.com/@drjoshaxe?sub_confirmation=1

 

🎧 Early Access!

Our listeners enjoy every episode before anyone else! Tune in below and join our exclusive group of listeners →

Spotify: https://bit.ly/DrJoshAxeSpotify

Apple Podcast: https://apple.co/3JDvWcS

 

Pre-order my NEW BOOK, Heal Your Cells → healyourcellsbook.com

 

Watch my free training on how to naturally balance your blood sugar and reverse your symptoms → http://DrAxeDiabetesClass.com

 

Discover practical steps you can take today to start healing your thyroid naturally →   http://DrAxeThyroidClass.com

 

If you’re ready to start feeling like yourself again and balance your hormones, take my free class → http://DrAxeHormoneClass.com

 

CONNECT WITH DR. JOSH AXE

Instagram → https://www.instagram.com/drjoshaxe/

Facebook → https://www.facebook.com/DrJoshAxe/

TikTok → https://www.tiktok.com/@thedrjoshaxeshow/

X → https://x.com/drjoshaxe/

LinkedIn → https://www.linkedin.com/in/joshaxe

Website →  http://thehealthinstitute.com

Sign up for my newsletter → https://bit.ly/4oE9Jf3

Ask Dr. Axe → http://speakpipe.com/drjoshaxe 

 

0:00 Introduction & Luke 8:17

1:26 The Fauci Texts: COVID Vaccines and Miscarriage Risk

5:10 Israeli & Scottish Study Data on Fetal Loss After mRNA Vaccination

8:40 How Cytokine Storms Affect Early Pregnancy

10:30 The Reframe: Fertility as a Downstream Body Signal

13:35 Root Cause #1 — Blood Sugar & Insulin Resistance

17:41 Root Cause #2 — Thyroid Antibodies (The Marker Most Doctors Skip)

18:50 Root Cause #3 — Nutrient Deficiencies (Vitamin D, Iron, B12, Zinc)

20:30 Root Cause #4 — Stress & Safety Signals

22:50 Root Cause #5 — Endocrine Disruptors & Environmental Chemicals

24:56 Root Cause #6 — Male Fertility & Falling Sperm Counts

26:24 The 10-Marker Fertility Blood Panel

28:44 Chinese Medicine Lens: Kidney Yang, Blood Stagnation & Damp Phlegm

35:57 Supplements, Sleep, and the 90-Day Reset Plan

 

 

DISCLAIMER

This content is strictly the opinion of Dr. Josh Axe and is for informational and educational purposes only. It is not intended to provide medical advice or to take the place of medical advice or treatment from a personal physician. All viewers of this content are advised to consult their doctors or qualified health professionals regarding specific health questions. Neither Dr. Axe nor the publisher of this content takes responsibility for possible health consequences of any person or persons reading or following the information in this educational content. All viewers of this content, especially those taking prescription or over-the-counter medications, should consult their physicians before beginning any nutrition, supplement or lifestyle program.

 

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