Dhru Purohit Show

• Neurophysiologist Shares Top 3 Drivers of Alzheimer’s Disease, How To Reduce Your Risk of Cognitive Decline At Any Age, and How to Build a Super-Brain with Louisa Nicola (Rebroadcast)

  This episode is brought to you by Momentous, Levels, and Branch Basics. Alzheimer’s doesn’t begin at diagnosis—it starts decades earlier. That means the choices we make right now can have a major impact on our brain health down the line. But with so much conflicting health advice out there, how do you know what really moves the needle? Today’s guest cuts through the noise and shares the most effective, science-backed strategies to protect your brain, no matter your age. Today on The Dhru Purohit Show, we’re revisiting one of our favorite episodes with neurophysiologist Louisa Nicola. Louisa shares the top three lifestyle factors that can influence our risk for Alzheimer’s disease. She helps us sort through the most current research and uncovers the biggest myths. She also shares the top two supplements that are critical for protecting brain health and the optimal prescription for exercise and resistance training. Looking to protect your brain health? Louisa shows us how. Louisa Nicola, an Australian-born neurophysiologist and sports scientist, has made significant strides in the field of brain performance and human potential. In 2016, she founded Neuro Athletics, a consulting firm dedicated to optimizing brain health and performance for athletes, executives, and high performers. Louisa's innovative methods improve reaction times, decision-making, and mental acuity. Her vision is to expand Neuro Athletics' reach, empowering more individuals to achieve their full potential through enhanced brain function and mental resilience. In this episode, Dhru and Louisa dive into: The alarming increase in Alzheimer's disease despite genetics (00:33) Why sleep is a critical factor in preventing disease (2:43) The impact of a sedentary lifestyle on increasing your risk for Alzheimer’s disease and tips for beginners (17:47) Physiology as we age (34:35) Fundamental pillars of nutrition and the power of Omega-3 fatty acids (42:20) Creatine for neuroprotection, energy, and reversing osteoporosis (54:02) The biggest myth about Alzheimer’s disease (01:02:51) What motivated Louisa to study Alzheimer’s disease (01:05:44) Actionable steps you can implement to reduce your risk (01:08:50) Implementing sauna into your routine to induce good stress (01:12:13) Brain optimization beyond the fundamentals (01:15:12) Social connections that power health (01:23:18) Bigger muscles-better brain health (01:31:20)  Also mentioned in this episode: Omega Quant Test Neuroathletics Instagram Sleep Regularity as a Predictor of All-Cause Mortality Study  For more on Louisa, follow her on Instagram, Twitter, and YouTube, or visit her Website. This episode is brought to you by Momentous, Levels, and Branch Basics. Optimize your energy and mental clarity with the Momentous Three: Protein, Omega-3s, and Creatine made by and used by the best. Head to livemomentous.com and use code DHRU for 35% off your first subscription. Right now, Levels is offering my listeners an additional 2 FREE months of the Levels annual Membership when you use my link: levels.link/DHRU. Make moves on your metabolic health with Levels today. Right now, Branch Basics is offering 15% off the Premium Starter Kit; just go to branchbasics.com and use coupon code DHRU. Make 2025 your cleanest, healthiest year yet with Branch Basics! Sign up for Dhru’s Try This Newsletter Learn more about your ad choices. Visit megaphone.fm/adchoices

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• The Labs You Need Your Doctor to Run to Know if Your Metabolically Healthy

  This episode is brought to you by Square, Branch Basics, and Manukora Honey. When we’re told our labs are “normal,” that doesn’t always mean they’re optimal—especially considering that over one-third of Americans are prediabetic and 47 million have metabolic syndrome. Metabolic health is the foundation of true longevity. Without actively supporting it, the risk of chronic diseases like cardiovascular disease, cancer, and type 2 diabetes increases. The good news? Prioritizing metabolic health through simple lifestyle changes can lead to long-term vitality and meaningful transformation. Today on The Dhru Purohit Show, we’re bringing you a special compilation episode featuring Dhru’s conversations with top experts on the most underrated blood tests for metabolic health and how to decode optimal lab markers. Dr. Tyna Moore breaks down the science behind metabolic dysfunction and its connection to chronic disease. She shares the essential labs to order, how often to test, and what optimal results should look like. She also offers practical tips for beginners on getting started with resistance training. Dr. Ben Bikman dives into how elevated fasting insulin contributes to insulin resistance, fat storage, and challenges in sustainable weight loss. He also explores how genetics play a role in weight gain and why lowering insulin—not just counting calories—should be the first step in any effective weight-loss strategy. Dr. Tyna Moore is a board-certified naturopathic and chiropractic physician and the founder and owner of Core Wellness Clinic in Portland, Oregon. She specializes in non-surgical pain management, natural pain solutions, and regenerative injection therapies for orthopedic and musculoskeletal conditions.  Dr. Ben Bikman is a metabolic research scientist and author of Why We Get Sick, which explores insulin resistance as a root cause of many chronic health issues. With a PhD in bioenergetics and postdoctoral work in metabolic disorders, he now serves as an associate professor at BYU, where he studies insulin’s role in obesity, diabetes, and mitochondrial health. In this episode, Dhru and his guests dive into: Metabolic health and disease pathways (2:10) Key lab tests and optimal levels (4:25) How and why to start resistance training (20:49) The most underrated blood test for metabolic health (33:57) Optimal reference ranges for fasting insulin (37:45) The two primary factors contributing to weight gain (44:22) The role of fat cells and ethnic differences (53:09) Final thoughts (1:01:34) Also mentioned: Full episode with Dr. Tyna Moore Full episode with Dr. Ben Bikman Want Dhru’s Lab Ranges Cheat Sheet? Sign up for the Try This Newsletter and we’ll send it straight to your inbox! This episode is brought to you by Square, Branch Basics, and Manukora Honey. Get everything you need to run and grow your business, without any long-term commitments with Square. Right now, you can get up to $200 off Square hardware at square.com/go/DHRU Right now, Branch Basics is offering 15% off the Premium Starter Kit; just go to branchbasics.com and use coupon code DHRU. Make 2025 your cleanest, healthiest year yet with Branch Basics! Upgrade to the creamiest honey, packed with antioxidants and prebiotics. Just go to manukora.com/dhru to get $25 off the Starter Kit and boost your energy, immunity, and digestive health today! Sign up for Dhru’s Try This Newsletter Learn more about your ad choices. Visit megaphone.fm/adchoices

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• Integrative Doctor Shares the Dangers of Microwaving Plastic, Eating Canned Foods and Top Sources of Endocrine Disruptors and How Simple Swaps in Our Home Make a Huge Difference with Dr. Vivian Chen

  This episode is brought to you by Lumebox, Cozy Earth, and Ollie. We don’t often think of our homes as a source of toxins—but many of the most common exposures are hiding right where we cook, eat, breathe, and sleep. Not sure where to start when it comes to removing them? You’re not alone. Today’s guest is here to simplify the process, breaking down the top toxin exposures with a tiered ranking and showing you exactly what to remove, replace, or swap first for the biggest impact. Today on The Dhru Purohit Show, Dhru sits down with Dr. Vivian Chen to uncover the top sources of toxins hiding in your home. Dr. Chen shares must-do swaps in the kitchen, covering everything from cookware and food storage to baking essentials. She also offers practical tips to support your body’s natural detoxification and elimination process through simple lifestyle habits. Dr. Chen dives into the hidden toxins in feminine hygiene products and the safer alternatives. If you’re looking for simple, actionable strategies to reduce your daily exposure to toxins, this episode is a must-listen.   Dr. Vivian Chen (MBBS, MRCP, MRCGP) is a UK-trained medical doctor with 15 years of clinical experience in internal medicine and family practice, and the co-founder of LUMEBOX, the leading portable red light therapy company. Now based in California, she traded her prescription pad for a deeper mission: helping people uncover and address the root causes of their health struggles—from mitochondrial dysfunction to environmental toxicity. In this episode, Dhru and Dr. Chen dive into: The best and worst types of cookware (00:24) The connection between cooking with cast iron and iron levels (4:02) Common sources of endocrine disruptors (5:05) Microwave-safe plastic containers and recommended changes when using plastic (8:15) Canned foods and how toxic exposure can vary based on your choices (14:55) Top sources of toxins in daily life and how to improve indoor air quality (18:12) The dangers of using aluminum foil to wrap food (29:13) Unbleached parchment paper, silicone cookware, and stainless steel storage (35:09) Constipation, detoxification, and the importance of tracking fiber intake (46:13) Exercise and its full-body detoxification benefits (56:53) How to support the body’s natural detoxification pathways (59:58) Different types of saunas and their detox benefits (1:08:21) Red light therapy: how to use it and its full-body benefits (1:12:18) How sleep supports detoxification and the top causes of poor sleep (1:21:48) The risks of using paper cups daily and the benefits of reusable alternatives (1:34:08) Why conventional paper receipts pose health risks (1:36:53) How scented candles impact indoor air quality (1:39:32) The effects of traditional feminine hygiene products on health (1:41:48) Final thoughts and where to follow Dr. Chen’s work (1:56:56) Also mentioned in this episode: EWG  Bristol Stool Chart  Lupini Beans King Grove Organic Farm  Try This: Surprising Findings from a Major Report On Microplastics For more on Dr. Chen, follow her on Instagram, LinkedIn, and her Website. This episode is brought to you by Lumebox, Cozy Earth, and Ollie. Lumebox is offering my community $280 off their FDA-registered portable Red Light device!  That's over 44% off! Go to thelumebox.com/dhru and get your Red Light device. Right now, get 40% off your Cozy Earth sheets. Just head over to cozyearth.com/dhru and use code DHRUP. Want to give your dog the best in clean eating? Take the online quiz and introduce Ollie to your pet. Right now, Ollie is offering 60% off your first box of meals when you subscribe today! Just head to Ollie.com, use the code DHRU, and you’ll get 60% off your first box of meals in your subscription. Sign up for Dhru’s Try This Newsletter Learn more about your ad choices. Visit megaphone.fm/adchoices

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  2:01:13
• How to Make It To 100 With A Sharp Brain And Good Mobility

  This episode is brought to you by One Skin, Bon Charge, and Manukora Honey. As we age, many of us worry about losing the ability to move freely or manage daily tasks—and with Alzheimer’s on the rise, cognitive decline is a growing concern too. But here’s the good news: just as we can preserve mobility well into our later years, we can also maintain a sharp, healthy mind. Today on The Dhru Purohit Show, we’re bringing you a special compilation episode featuring Dhru’s conversations with leading experts on how to live a vibrant life into your 100s. Dr. Dale Bredesen explains why cognitive decline is no longer a mystery—and why it’s not an inevitable part of aging. He emphasizes the importance of early prevention and shares seven foundational strategies to help protect your brain decades before symptoms appear. Juliet and Kelly Starrett join Dhru to share their practical, no-frills approach to promoting durability and mobility as we age. They cover simple at-home mobility tests like the sit-and-rise test. Their insights show how small, consistent changes in diet and movement can lay the foundation for lasting vitality and a body that recovers well from setbacks as you grow older. Dr. Dale Bredesen is internationally recognized as an expert in Alzheimer’s disease and is the author of several New York Times bestsellers.. He serves as the principal investigator for the Alzheimer’s Disease Research Center at UCLA and founded the Alzheimer’s Drug Development Network in 2008, which helped identify new therapeutics for the disease.  Juliet Starrett is an entrepreneur, attorney, author, podcaster, and professional whitewater paddler, winning three world championships and five national titles. Dr. Kelly Starrett consults with elite athletes and coaches. Juliet and Kelly Starrett founded The Ready State fitness podcast and blog, San Francisco CrossFit, and are co-authors of the Wall Street Journal bestseller Deskbound and the New York Times bestseller Built to Move.  In this episode, Dhru and his guests dive into: Cognitive decline and ways to reduce the risk of developing Alzheimer’s (1:30) Exposure to biotoxins that contribute to cognitive decline (5:02) The link between mold toxicity and Alzheimer’s disease (10:58) Foundational diet and lifestyle strategies for Alzheimer’s prevention (20:12) How the brain uses energy—and why it matters (25:37) Tips for improving sleep quality (33:17) How to manage mental stress and perceived threats (36:39) The importance of taking high-quality fish oil daily (41:17) Why the sit-and-rise test is a key indicator of longevity (43:58) Major milestones when declines in mobility typically begin (52:40) Factors that influence long-term mobility (56:03) Supporting mobility for everyday movement and independence (1:01:33) At-home tests to assess your range of motion (1:05:54) Final thoughts and key takeaways (1:12:20) Also mentioned: Full episode with Dr. Dale Bredesen Full episode with Dr. Kelly & Juliet Starrett This episode is brought to you by One Skin, Bon Charge, and Manukora Honey. Right now, One Skin is offering my community 15% off; just go to oneskin.co and use coupon code DHRU to save 15% and give your skin the scientifically proven, gentle care it deserves. Right now, Bon Charge is offering my community 15% off; just go to boncharge.com/DHRU and use coupon code DHRU to save 15%. Upgrade to the creamiest honey, packed with antioxidants and prebiotics. Just go to manukora.com/dhru to get $25 off the Starter Kit and boost your energy, immunity, and digestive health today! Sign up for Dhru’s Try This Newsletter Learn more about your ad choices. Visit megaphone.fm/adchoices

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  1:10:16
• How to Get Fit for Summer: Ranking the Best and Worst Health Trends of 2025 including Fasting, Creatine and Detox Diets with Cynthia Thurlow

  This episode is brought to you by Momentous, Our Place, and Maui Nui. When it comes to intermittent fasting and sustainable weight loss, the advice out there can be overwhelming and often conflicting. Today’s guest joins the podcast to cut through the noise and tier-rank the most effective lifestyle strategies for long-term success, spotlighting what truly moves the needle—and what’s better left behind. Today on The Dhru Purohit Show, Dhru sits down with Cynthia Thurlow to unpack what we need to prioritize—and just as importantly, what to let go of—for sustainable weight loss and long-term weight management. Together, they tier-rank the most impactful lifestyle habits and debunk common myths around overexercising, one-meal-a-day diets, and detox trends. Cynthia also challenges outdated narratives targeted at men and women over 40, offering a science-backed approach to behavior change. Plus, she dives into the most destructive mindsets that often lead to self-sabotage. Cynthia Thurlow is a nurse practitioner, author, and host of the Everyday Wellness podcast. With over 25 years in health and wellness, she’s a leading expert in intermittent fasting and women’s health during perimenopause and menopause. Her TEDx talk on intermittent fasting has over 15 million views. Cynthia’s mission is to empower women to thrive through midlife and beyond. In this episode, Dhru and Cynthia dive into: Role and benefits of intermittent fasting in weight loss (00:24) Long-term goals for fasting (4:08) Counting and tracking macros (5:36) The downsides of the one-meal-a-day (OMAD) trend (11:15) The connection between body parasites and weight loss (20:24) Gut health tests and their impact on weight loss (25:22) “Thyroid-pause” and its effect on weight (33:26) The role of fiber in our diet and its impact on the microbiome (41:16) Detoxing for weight loss—does it help? (43:05) The difference between intense daily cardio and strength training (51:10) Daily alcohol consumption and its effect on weight loss (1:00:25) Regular and diet soda consumption—how they affect the body (1:03:45) The role of mindset in a successful weight loss journey (1:09:28) Recommendations for developing a stronger mindset (1:12:48) Destructive beliefs that sabotage wellness goals (1:15:16) Why a daily dose of creatine matters (1:17:32) The role of protein powders and shakes in your diet (1:21:49) Seed oils and how to reduce ultra-processed food intake (1:25:05) Thoughts on GLP-1 medications (1:35:25) Hormone replacement therapy (1:47:44) Cynthia’s practical steps for sustainable weight loss and building strength (1:55:01) Also mentioned in this episode: Everyday Wellness with Cynthia Thurlow ™ - Podcast Cynthia's Creatine - The Midlife PAUSE: Strength, Radiance, and Resilience Dhru's protein shake: Try This newsletter For more on Cynthia, follow her on Facebook, Instagram, X/Twitter, YouTube, TikTok, LinkedIn, and her Website. This episode is brought to you by Momentous, Our Place, and Maui Nui. Optimize your energy and mental clarity with the Momentous Three: Protein, Omega-3s, and Creatine made by and used by the best. Head to livemomentous.com and use code DHRU for 35% off your first subscription.  Reduce your toxic load by upgrading your cookware! Go to fromourplace.com today and use promo code DHRU at checkout to receive 10% off any order. Right now, Maui Nui Venison is offering my listeners a limited collection of my favorite cuts and products. Just go to mauinuivenison.com/dhru to secure your access now —but hurry, supply is limited! Sign up for Dhru’s Try This Newsletter Learn more about your ad choices. Visit megaphone.fm/adchoices

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