PodcastsHealth & WellnessPeptide of The Week

Peptide of The Week

JD Denham and Will Haas
Peptide of The Week
Latest episode

109 episodes

  • Peptide of The Week

    Peptide Q&A #48 – Diet for Women Over 50, Sleep Deprivation, TRT Pros & Cons & Gut Healing

    2026-07-02 | 55 mins.
    Medical Disclaimer: We are not doctors. The content in this video is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk.

    Welcome back, warriors! In this week's Peptide Q&A, JD Denham (live from Cabo) and William T. Haas cover diet and exercise for women over 50, surviving on two to three hours of sleep, TRT pros and cons, mixing peptides in bulk vials, gut healing miracles, and how peptides are actually made.

    Chapters
    00:00 – Cabo Update & Will's Wedding Prep
    03:52 – Weight Loss: Diet vs. Peptides
    11:28 – Can You Survive on 2–3 Hours of Sleep?
    15:20 – Mixing Multiple Peptides the Right Way
    18:13 – Healing Chronic Gut Issues with Peptides
    22:17 – HGH for Women Over 60
    24:49 – Is TRT Worth It? Pros & Cons Explained
    31:15 – Recovering Faster from Training & Injuries
    35:03 – Productivity Guilt, Family & Finding Balance
    41:08 – Brain Fog, Focus & Cognitive Peptides
    45:08 – How Peptides Are Actually Made
    52:37 – Upcoming Guests & What's Next

    We cover:
    • Diet & Exercise for Women Over 50: Why resistance training beats cardio every time, why protein is the non-negotiable, and how lifting weights raises metabolism for 24 hours after the workout
    • Surviving on 2-3 Hours of Sleep: Why DSIP, SS-31, MOTS-C, TA-1 and NAD can help but won't save you long term and why Modafinil was literally made for shift work disorder
    • Pre-Filling a Week's Worth of Peptides in One Vial: Why the math works perfectly for SS-31 and MOTS-C and which compounds should never be mixed with others
    • Gut Healing Miracle on BPC & KPV: Why these two are the real healers inside Clow, why oral versions work well for gut-specific issues, and how long you can safely run them
    • HGH at 65 for a Female on HRT: Why secretagogues likely won't cut it at this age, why 1 IU of exogenous HGH is the right call, and how to get access
    • TRT at 43 with 560 Total Testosterone: Full breakdown of pros, cons, estrogen management, DHT and hair loss risk, and why free testosterone of 12 is the real problem
    • Recovery Stack for a 41-Year-Old Muay Thai Athlete: Why a Tesamorelin/Ipa or CJC/Ipa blend is the top recovery addition and why TRT status changes the whole answer
    • Productivity Guilt as a Sober Dad: Why blocking family time like a work appointment works, why rest is actually production, and why not drinking is the most important decision you're making
    • ARA-290 for Neuropathic Pain: Why this peptide has promise for nerve pain and why JD and Will are testing it soon
    • How Peptides Are Actually Made: Solid phase peptide synthesis explained simply, why raws all come from China, why BPC can never be patented, and what the FDA's clinical trial rules actually protect

    You're a warrior. Act like one.

    Follow us on social media:
    JD's Instagram: https://www.instagram.com/jddenhamofficial/
    Will's Instagram: https://www.instagram.com/williamthaas/
    Join The Community: https://www.skool.com/peptideresearchinstitute/about
    Subscribe to our Newsletter: https://potwnewsletter.beehiiv.com/
  • Peptide of The Week

    Peptide of the Week: The Godfather of Peptides With Trevor Kruder

    2026-06-29 | 1h 16 mins.
    Medical Disclaimer: We are not doctors. The content in this video is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk.

    Welcome back, warriors! In this episode of Peptide of the Week, JD Denham and William T. Haas sit down with Trevor Kruder the man they call the Godfather of Peptides. 12 years in the industry before most people knew what a peptide was, Trevor has built one of the most comprehensive peptide and hormone companies in the world. This one is packed.

    Chapters
    00:00 – Intro, Travel Plans & Life Updates
    06:29 – Hormones vs. Peptides: Where to Start
    13:30 – How Trevor Built a Peptide Empire
    18:18 – Hiring Great People & Building Teams
    22:23 – Is It Too Late to Start a Peptide Business?
    31:36 – Leadership, Growth & Managing Success
    37:28 – Social Media, Misinformation & Peptides
    41:05 – Why China Dominates the Peptide Industry
    46:22 – The Reality of Starting a Peptide Company Today
    50:52 – Educating Doctors & Growing the Industry
    53:08 – The Future of Peptides & Telehealth
    57:20 – Final Thoughts & Closing Advice

    We cover:
    🏗️ How it all started
    – Started synthesizing peptides from scratch 12 years ago with $30,000 and a small lab
    – Spent 7 years building with almost no market nobody knew what peptides were
    – Built a 20,000 doctor network and scaled to $170–180M in under 2 years
    – Now operates 44+ companies including telehealth, pharmacies, drug manufacturing, research, cosmetics, hair restoration, and more
    – 500–800 employees across multiple sites

    🏥 What he's built
    – Three telehealth companies and three 503A pharmacies
    – 50-state hormone license supplies Walgreens, CVS, and rare disease medications to every major university in the US
    – Two 503B sterile injectable facilities (two more being built)
    – Research manufacturing sites running 12–14 IRBs and INDs per year
    – AlphaSync described as Amazon for doctors, full platform for ordering peptides and hormones at a fraction of market cost
    – New brick-and-mortar wellness center opening: IV, hyperbaric, red light, full gym, laser treatments all under a membership model

    🔬 What's coming — peptides to watch
    – FLGR-242 (Follistatin 242): modified follistatin that actually adds muscle one of the most exciting muscle builders emerging
    – Lepto: GLP + GIP + Glucagon + IGF-1 once every two weeks injection, helps with weight loss while protecting muscle from wasting
    – Albumin-bound semaglutide: 1/10th the normal dose with the same result no receptor burnout
    – Oral peptide delivery system: coats peptide to survive digestion, bypasses liver, enters lymphatic system 24x more bioavailable in models. Human trials starting in 30 days

    🌏 The peptide industry reality
    – China makes 80% of the world's peptide raw materials and that's not changing their facilities cost $300M–$1B+
    – Finished goods manufacturing in China is technically not legal enforcement is ramping up as China wants revenue
    – American API manufacturing is nearly impossible due to environmental regulations and cost
    – Anyone entering the industry now needs real money, real testing, and real infrastructure — the easy days are over
    – Janoshik-style third party testing is now essential fake, empty, and underdosed vials are flooding the market

    📺 Subscribe for more no-fluff peptide education every week.

    Follow us on social media:
    JD's Instagram: https://www.instagram.com/jddenhamofficial/
    Will's Instagram: https://www.instagram.com/williamthaas/

    Follow Trevor Kruder:
    Website: https://alphabiomedlabs.com
    Website: https://www.trevorkruder.com
    Instagram: https://www.instagram.com/trevorkruder

    Join The Community: https://www.skool.com/peptideresearchinstitute/about
  • Peptide of The Week

    Peptide Q&A #47 – TRT & Hair Loss, Blood Work Panels, HCG vs Clomid & Autoimmune

    2026-06-25 | 1h 4 mins.
    Medical Disclaimer: We are not doctors. The content in this video is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk.

    Welcome back, warriors! In this week's Peptide Q&A, JD Denham and William T. Haas cover TRT and hair loss fears, severe histamine reactions, HCG vs Clomid for fertility on TRT, autoimmune protocols, building muscle with Charcot-Marie-Tooth disease, and cognitive function peptides for older men.

    Chapters:
    00:00 – Fatherhood, Family & Travel Plans
    07:05 – Relationships, Marriage & Commitment
    14:29 – New Producer & Community Update
    17:18 – TRT, Hair Loss & Optimization
    24:18 – Gut Health & Autoimmune Peptides
    28:37 – Healing Shoulder Injuries with Peptides
    32:35 – Retatrutide Progress & Weight Loss
    37:23 – Growth Hormone, Longevity & Brain Health
    42:58 – TRT Protocols, Fertility & HCG
    50:52 – Preserving Muscle After 50
    54:34 – Histamine Reactions & Injection Issues
    58:23 – Autoimmune Support & Closing Thoughts

    We cover:
    • TRT & Hair Loss at 47: Why DHT is the culprit, why a very low starting dose may minimize the risk, and why how you feel should outrank how much hair you have
    • Autoimmune, Gut Healing & Inflammation: Why oral BPC and KPV beat Klow for gut-focused protocols, the TA-1 and LL-37 VIP sequence for autoimmune, and what to watch for during flares
    • Shoulder Stabilization Recovery at 21: Why aggressive daily dosing of BPC and TB-500 beats conservative approaches and why movement accelerates healing
    • Retatrutide Not Moving the Scale: Why feeling leaner and weight staying flat means body recomposition is working and why itchy skin typically resolves on its own
    • Blood Work Panels for a 64-Year-Old: Why DEXA scan, IGF-1, ApoB, ferritin, thyroid panel and homocysteine matter most and where to find the full list in the school
    • TRT at 33 with Testosterone at 145: Why N-Clomiphene beats Clomid, when to use HCG vs when to save it for fertility, and how to read early estrogen warning signs
    • Building Muscle with Charcot-Marie-Tooth & Post-Menopause: Why adding Ipa to Tesamorelin, cycling IGF-1 LR3 short term, and potentially pulling Retatrutide to eat more may be the real answer
    • Severe Full-Body Histamine Reaction: Why CJC is the most common culprit, how to systematically reintroduce one compound at a time, and why slower injection into fat reduces reactions
    • Chilblains & Cold Feet from Autoimmune: Why KPV injectable, TA-1, Wolverine and oral BPC beat prescription antibiotics for this condition
    • Cognitive Function Peptides at 64: Why Dihexa, Pinealon, Cerebrolysin, Semax, Selank and Modafinil are the right tools and how they each work differently on the brain

    📌 Subscribe for weekly, no-fluff protocols, dosing guidance, and real-world results.

    You're a warrior. Act like one.

    Follow us on social media:
    JD's Instagram: https://www.instagram.com/jddenhamofficial/
    Will's Instagram: https://www.instagram.com/williamthaas/
    Join The Community: https://www.skool.com/peptideresearchinstitute/about
    Subscribe to our Newsletter: https://potwnewsletter.beehiiv.com/
  • Peptide of The Week

    Peptide of the Week: Best Peptides & Compounds to Build Muscle

    2026-06-22 | 45 mins.
    Medical Disclaimer: We are not doctors. The content in this video is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk.

    Welcome back, warriors! In this episode of Peptide of the Week, JD Denham and William T. Haas go head to head with their personal muscle building stacks without comparing notes. Will focused on pure muscle building peptides. JD approached it from a full body recomposition angle. Same goal, two very different minds.

    Chapters:
    00:00 – Fatherhood, Family & God Shots
    09:03 – Top Peptides for Building Muscle
    11:07 – IGF-1 LR3 & HGH Explained
    14:10 – Tesa, Ipamorelin & CJC-1295
    19:02 – BPC-157, TB500 & Recovery
    21:25 – JD's Muscle-Building Stack
    25:28 – MK-677, Fat Loss & Performance
    29:40 – Peptides vs Steroids
    33:03 – Favorite Cutting Cycles
    40:28 – Why Everyone Should Take Creatine
    43:02 – Skool Community & Final Thoughts

    We cover:
    💪 Will's Top 5 Muscle Building Peptides
    – IGF-1 LR3: the downstream effect of HGH this IS what builds muscle. Best used post-workout with protein and carbs. 8 weeks max
    – HGH: increases IGF-1, burns fat, grows tissue everywhere hair, nails, recovery. The long game
    – PEG-MGF: local IGF-1 equivalent inject directly into the muscle you just trained post-workout for localized growth
    – Tesamorelin + Ipamorelin: GHRH + GHRP combo increases natural HGH pulses, burns visceral fat, FDA approved. Nearly interchangeable with CJC-1295 + Ipamorelin
    – CJC-1295 No DAC: mirrors natural HGH pulses, safer long-term than DAC version
    – Honorable mention: Follistatin 344 / Myostatin Inhibitor theoretical but exciting. Modified version (Follistatin 242) more targeted. Still early in human data

    🏋️ JD's Get-In-Shape Stack
    – Testosterone: the non-negotiable base for anyone over 40. Hormonal optimization first
    – HGH (2 IU morning, fasted): better sleep immediately, long-term fat burning and recovery
    – MK-677: closest thing to gear without gear. Increases appetite, nutrient partitioning, fullness, and sleep quality. Pairs well with Retatrutide if hunger becomes an issue
    – 5-Amino-1MQ: keeps fat burning active while adding carbs for muscle growth
    – Wolverine Stack (BPC-157 + TB-500): mandatory for anyone lifting heavy over 40. You cannot build without recovering
    – Creatine HCL (3g daily): most studied supplement available. Strength, endurance, cell hydration, muscle growth men and women should take it

    ⚗️ Gear Curveball — Cutting Stack (JD)
    – Testosterone (low, as base only)
    – Winstrol injectable (weeks 1–4)
    – Masteron (add at week 2, run 2 months)
    – Proviron (enhances everything, releases free testosterone)
    – Optional: Anavar at the end or in place of Winstrol

    ⚗️ Gear Curveball — Muscle Stack (Will)
    – Testosterone Sustanon 400mg (blend of 4 esters, hits in waves)
    – Turinabol 25–50mg daily as kickstart (6 weeks max) — leaner, more athletic than D-ball
    – Primobolan or Masteron at 2:1 ratio vs testosterone — low side effects, no water retention
    – Proviron in last 3/4 of cycle — peels SHBG off receptors, everything feels enhanced again
    – 400mg = anabolic threshold / 800mg = upper limit where receptors are maxed

    💡 Real talk
    – Peptides alone will not pack on size like gear that's just the truth
    – But peptides have an elite safety profile gear cannot match
    – Sleep and protein are non-negotiable no stack replaces them
    – Creatine HCL over monohydrate for less bloat same results
    – Never run gear without testosterone as a base everything shuts you down without it

    📺 Subscribe for more no-fluff peptide education every week.

    Follow us on social media:
    JD's Instagram: https://www.instagram.com/jddenhamofficial/
    Will's Instagram: https://www.instagram.com/williamthaas/
    Join The Community: https://www.skool.com/peptideresearchinstitute/about
    Subscribe to our Newsletter: https://potwnewsletter.beehiiv.com/
  • Peptide of The Week

    Peptide Q&A #46 – Peptide Legalities, Carnivore on Reta, Sleep Quality & Histamine Reactions

    2026-06-18 | 1h 16 mins.
    Medical Disclaimer: We are not doctors. The content in this video is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk.

    Welcome back, warriors! In this week's Peptide Q&A, JD Denham and William T. Haas cover the legalities of peptides for police officers, why Tesamorelin timing changes when combined with Retatrutide, carnivore dieting on GLP-1s, anaphylactic reactions, sleep tracking pitfalls, and protocols for chronic injuries and cough.

    Chapters:
    00:00 – Travel Plans & Business Updates
    10:45 – Peptide Legalities & First Responder Policies
    16:44 – Tesa, RETA & Timing Protocols
    27:13 – Surgery Recovery & Wolverine Stack
    31:45 – Carnivore Diet, RETA & Performance
    45:16 – Discipline, Cravings & Staying Lean
    45:39 – Sleep Problems, Cortisol & Recovery
    53:29 – Mixing Peptides for Simplicity
    57:40 – Healing Old Injuries & Scar Tissue
    59:21 – Histamine Reactions & Tesa Concerns
    1:03:47 – Chronic Cough, Gut Health & Inflammation

    We cover:
    • Peptides & Police Officer Liability: Why department conduct codes matter more than legality and why selling vs. using makes a real difference
    • Tesamorelin + Retatrutide Timing: Why insulin blunts Tesamorelin's effects and why morning dosing may now beat the old nighttime recommendation
    • Pre-Surgery Healing Protocol: Why Klow plus high-dose Wolverine blend beats either alone and how to layer GHK-CU and Snap-8 for scarring
    • Carnivore Diet While on Retatrutide: Why full carnivore still works, the gallstone and electrolyte risks to watch, and why objectives determine the approach
    • Sleep Tracker Anxiety & Perimenopause: Why obsessing over Garmin scores can backfire and why high cortisol explains negative vivid dreams
    • Combining Peptides for Elderly Parents: Why mixing SS-31/C-Max and Klow/Tesamorelin in one syringe is fine and when cloudiness signals a problem
    • Old Chronic Ankle Injury: Why TB-500 wakes up dormant injuries that have stopped trying to heal themselves
    • Anaphylactic Reaction After Tesamorelin: Why a one-hour delay makes it an unlikely culprit and why an allergist panel is the smart next step
    • Chronic Cough & Suspected Lung Infection: Why gut health may be the root cause and the Thymosin Alpha-1/LL-37/VIP protocol to try before antibiotics
    • Postpartum Weight Loss & Tesamorelin Timing: Why giving Retatrutide more time before adding Tesamorelin makes sense at only three weeks in
    • Hiding Retatrutide Use from Others: Why discipline beats secrecy and why owning your peptide use beats lying to the people around you

    📌 Subscribe for weekly, no-fluff protocols, and real-world results.

    You're a warrior. Act like one.

    Follow us on social media:
    JD's Instagram: https://www.instagram.com/jddenhamofficial/
    Will's Instagram: https://www.instagram.com/williamthaas/
    Join The Community: https://www.skool.com/peptideresearchinstitute/about
    Subscribe to our Newsletter: https://potwnewsletter.beehiiv.com/
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About Peptide of The Week
Hosted by JD Denham and Will Haas, The Peptide of The Week Podcastis your no-BS guide to peptides, performance, and total body optimization. Whether you’re an athlete, a high performer, or just hungry to feel better, move better, and live stronger this show’s for you. JD and Will dive deep into real-world protocols, hard-earned lessons, and the science behind what actually works. With expert guests and raw conversations, you’ll get everything from cutting-edge peptide talk to diet, training, recovery, and mindset. No fluff. No filters. Just the tools to rebuild your body and upgrade your life.
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