Peptide of The Week

Medical Disclaimer: We are not doctors. The content in this video is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk.

Welcome back, warriors! In this week's Peptide Q&A, JD Denham and William T. Haas cover whether HGH and IGF-1 LR3 can be stacked safely, why libido stays low even on TRT, Wolverine protocols for a 69-year-old with nine surgeries, why peptides don't show on drug tests, and how to dose BPC and TB-500 for a 125-pound dog.

Chapters
00:00 – Intro
00:09 – Newport Dunes, Family Trip & Prague Plans
03:24 – The Future of Peptide Testing & COAs
09:32 – HGH vs. IGF-1: Should You Stack Them?
18:56 – Wolverine Stack for Surgery & Injury Recovery
22:00 – Healing the Gut with BPC-157 & KPV
26:45 – RETA, Weight Loss & High LDL Explained
30:27 – Why GHRHs & GHRPs Work Better Together
34:07 – Low Libido on TRT: What You're Missing
42:13 – Do Peptides Show Up on Drug Tests?
44:39 – RETA, Muscle Gain & Increasing Your Metabolism
50:58 – Ulcerative Colitis, Wegovy & Switching to RETA
53:16 – Using Peptides for Dogs & Surgery Recovery
55:56 – Peptides Before Surgery, Fasting Protocol & Community Updates

We cover:
• HGH + IGF-1 LR3 Together Safe or Not?: Why doubling up amplifies muscle building but also amplifies insulin sensitivity risk and who should and shouldn't do it
• Why GHRH and GHRP Work Better Together: How Sermorelin and Ipamorelin amplify each other's pulses and why Tesamorelin plus low-dose Ipa is the best combo for women prone to water retention
• 69-Year-Old LEO with Nine Surgeries: Why high-dose Wolverine is safe, why two migs of each daily post-surgery is the target, and why injecting close to the site matters
• Diverticulosis & Ulcerative Colitis Protocol: Why oral BPC and KPV are the foundation and why most medications are probably making the gut worse
• High LDL on Retatrutide in Women: Why rapid fat loss temporarily raises LDL, why it's not alarming at 106, and why the scale is the wrong metric to chase
• Low Libido at 44 on TRT: Why free testosterone matters more than total, why 100 migs may be too low, and why diet, sleep, cortisol and estrogen all outrank more testosterone
• Do Peptides Show Up on Drug Tests: Why no standard employment test screens for peptides and why the economics of testing make it nearly impossible
• Gastric Sleeve Patient Stalled at 145 Pounds: Why eating more protein not fewer calories is the fix and why adding Tesamorelin and Ipamorelin raises your BMR over time
• Switching Mom from Wegovy to Retatrutide: Why going pound for pound on dosage is the simplest approach and why she'll feel hunger again and that's okay
• Wolverine Protocol for a Saint Bernard Post Spinal Surgery: Why a human-sized dose is appropriate for a 125-pound dog, what the beagle studies show, and how to inject intramuscular

You're a warrior. Act like one.

Follow us on social media:
JD's Instagram: https://www.instagram.com/jddenhamofficial/
Will's Instagram: https://www.instagram.com/williamthaas/
Join The Community: https://www.skool.com/peptideresearchinstitute/about
Subscribe to our Newsletter: https://potwnewsletter.beehiiv.com/

Medical Disclaimer: We are not doctors. The content in this video is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk.

Welcome back, warriors! In this episode of Peptide of the Week, JD Denham and William T. Haas break down GHK-Cu, the Glow stack, and the Klow stack what they are, how they work, how to use them properly, and why they belong in almost everyone's protocol.

Chapters:
00:00 – Summer Plans, Travel & Prague Lab Visit
05:00 – Why Vacations Matter & Working Smarter
09:59 – Touring Janoshik Labs & Quality Testing
12:32 – GHK-Cu, Glow & Klow Explained
19:48 – How to Use GHK-Cu Face Serum Correctly
22:55 – GHK-Cu Shampoo & Hair Growth Benefits
29:04 – Why RETA Pairs Well with GHK-Cu
32:13 – Buffered Reconstitution & Reducing Injection Sting
33:51 – Glow vs. Klow vs. Wolverine Stack
46:09 – GHK-Cu Dosing, Cycling & Copper Safety
49:55 – Tattoos, Healing & Final Takeaways

We cover:
🧬 What is GHK-Cu?
– Copper peptide its primary job is signaling your body to produce more natural collagen
– Reduces and corrects skin inflammation
– Helps with wound healing, skin elasticity, fine lines, wrinkles, dark spots, and hair thinning
– GHK-Cu levels decline from ~200 ng/mL at age 20 to ~80 ng/mL at age 60 that decline shows up on your face
– Sub-Q injecting GHK-Cu has been shown to darken hair pigmentation — biochemically based, not hearsay
– GHK-Cu vs Minoxidil: GHK-Cu was found favorable in trials for hair growth
– A wound healing double-blind clinical trial on topical GHK-Cu serum is scheduled for 2026

💉 How to use the Face Serum correctly
– Use a dermal roller first opens the skin so it absorbs properly
– Clean the roller in alcohol before use
– Apply serum after rolling 3 days per week is the sweet spot
– Works if you just apply it, but works significantly better with the roller
– JD and his wife cut laser facial healing time in half using it friend who skipped the serum healed much slower
– Do NOT use numbing cream with the dermal roller Will learned this the hard way

🧴 GHK-Cu Shampoo
– Leave it in for 1.5–2 minutes before rinsing longer contact = better results
– Prolongs the hair follicle growth phase and stimulates thicker follicle growth
– Won't regrow hair on a completely bald scalp, but does make a noticeable difference
– A hairdresser in Orange County was blown away by results on her own thinning hair now sells it in her salon

🌟 Glow Stack (GHK-Cu + BPC-157 + TB-500)
– GHK-Cu: collagen production, skin repair, wound healing
– BPC-157: signaling peptide finds injuries, reduces inflammation, converts food into collagen building materials. Origin story: the peptide that prevents stomach acid from burning through your stomach lining
– TB-500 (Thymosin Beta-4): recruits stem cells, sends them where BPC-157 directs, reduces inflammation, accelerates tissue repair
– Together: BPC finds the problem, TB-500 sends the workforce, GHK-Cu builds the collagen

💪 Klow Stack (GHK-Cu + BPC-157 + TB-500 + KPV)
– Everything in Glow PLUS KPV for gut health
– KPV calms gut inflammation, helps leaky gut, modulates immune response
– Most autoimmune issues start in the gut KPV addresses the root
– Best all-in-one health and healing stack available

📺 Subscribe for more no-fluff peptide education every week.

Follow us on social media:
JD's Instagram: https://www.instagram.com/jddenhamofficial/
Will's Instagram: https://www.instagram.com/williamthaas/
Subscribe to our Newsletter: https://potwnewsletter.beehiiv.com/

Join The Community: https://www.skool.com/peptideoftheweekcommunity

Medical Disclaimer: We are not doctors. The content in this video is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk.

Welcome back, warriors! In this week's Peptide Q&A, JD Denham and William T. Haas cover why women respond differently to Retatrutide, how to mix multiple peptides into one vial, bulking stacks without anabolics, Crohn's disease protocols, loose skin after major weight loss, and long-term maintenance foundations.

Chapters:
00:00 – Prague Trip & Behind-the-Scenes Lab Tour
05:07 – Mixing Multiple Peptides Into One Injection
11:37 – RETA vs. Tirzepatide for Weight Loss
22:06 – Storing Peptides the Right Way
24:03 – Best Peptides for Energy, Anxiety & Cortisol
28:51 – Building Muscle Without Anabolics
36:18 – Injection Sites, TRT & Reducing PIP
41:00 – Loose Skin, Weight Loss & GHK-Cu
46:32 – Lean Bulking, IGF-1 & Muscle Growth
51:31 – Long-Term Maintenance & Favorite Stacks
56:45 – Crohn's Disease, Gut Health & BPC-157
1:00:01 – Fasting, Recovery & Final Takeaways

We cover:
• Mixing Multiple Peptides Into One Vial: Live demo of combining BPC, TB-500, KPV and Thymosin Alpha-1 for Will's mom the math, the method and what never to combine
• Wife Lost 100 Pounds on Tirzepatide but Stalled on Retatrutide: Why men lose faster, why she's probably not eating enough, and why Tesamorelin plus resistance training is the next move
• Peptide Storage Freeze or Refrigerate: Why freezing causes moisture risk and why the crisper drawer in the fridge is all you need for up to six months
• 24-Year-Old Female Always Tired & Anxious: Why eating more protein is likely the fix, why Selank and Semax are the right peptide pairing, and why blood work should come first
• Rotating Injection Sites & Scar Tissue: Why you must rotate within the same area, what scar tissue feels like, and why injection speed matters more than most people realize
• Loose Skin After Major Weight Loss: Why Klow, GHK-CU Snap-8 serum and Tesamorelin address it from every angle
• Lean Bulk Without Anabolics at 34: Why IGF-1 LR3, MK-677, creatine and high protein are the best non-anabolic stack and why Retatrutide works against a true bulk
• Retatrutide vs Tirzepatide for Wife Struggling with Food Noise: Why bumping Retatrutide slowly and adding resistance training beats switching back
• MOTS-C — Daily vs Three Times Weekly: Why there's no conclusive answer yet, why five migs at once can feel like pre-workout, and why Tesofensine is worth a trial
• Crohn's Disease Protocol: Why oral BPC and KPV are the first move, why carnivore and fasting give the gut a chance to heal, and why the liver needs rest too
• Long-Term Maintenance Foundation: Why TRT, HGH and occasional low-dose Retatrutide with hard work is all you ever really need

📌 Subscribe for weekly, no-fluff protocols, dosing guidance, and real-world results.

You're a warrior. Act like one.

Follow us on social media:
JD's Instagram: https://www.instagram.com/jddenhamofficial/
Will's Instagram: https://www.instagram.com/williamthaas/
Join The Community: https://www.skool.com/peptideresearchinstitute/about
Subscribe to our Newsletter: https://potwnewsletter.beehiiv.com/

Medical Disclaimer: We are not doctors. The content in this video is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk.

Welcome back, warriors! In this episode of Peptide of the Week, JD Denham and William T. Haas sit down with Josh Holyfield fitness coach, educator, and one of the most straightforward voices in the peptide and optimization space. This one gets into blood work patterns, the real problems with Western medicine, gear cycles, HGH science, and why most men are failing before they even start.

Chapters
00:00 – Meet Josh Holyfield
01:16 – From Fitness Coaching to Peptide Education
06:29 – Why He Walked Away from High-Ticket Coaching
10:04 – Why Traditional Medicine Falls Short
15:36 – The FDA, Pharma & the Future of Peptides
20:49 – Blood Work Every Man Should Understand
24:25 – Low Testosterone: Fix the Foundation First
28:23 – Helping Men Transform Their Lives
34:27 – Favorite Anabolics & Building Muscle
37:19 – Growth Hormone, IGF-1 & Recovery
45:10 – Optimizing Steroid Cycles Safely
55:11 – Enhanced Games, Sports & Final Thoughts

We cover:
🩺 What Josh actually sees on blood work
– Most men are walking around with total testosterone between 300–500 and most doctors think that's fine
– Low T is often a sleep and diet problem first not a TRT problem
– Elevated LDL on keto or RETA is expected your doctor doesn't know that
– APOB + HSCRP are better predictors of cardiovascular risk than LDL alone — and most doctors don't test for them
– Statins remove cholesterol the raw material your testicles use to make testosterone. Doctors prescribing statins to low T men are making the problem worse
– Women are almost universally under-eating this is the #1 issue Josh sees

🏥 Why Western medicine is failing
– Doctors aren't malicious they're programmed, incentivized, and legally constrained
– FDA is funded by the pharmaceutical companies it regulates
– Insurance companies dictate treatment guidelines not patient outcomes
– A drug that cures at 79% for $5 can't go to market if a 95% drug exists at $10,000 that's the law
– Peptide regulation is coming but so is more freedom for doctors to prescribe them

💉 HGH — the science behind timing
– GH converts to IGF-1 in the liver that's what builds muscle
– Insulin and IGF-1 compete take GH fasted so it can do fat burning and repair FIRST
– Morning dosing: just came off an 8-hour fast, pituitary still gets its natural 2–3AM pulse
– Night dosing: shuts down your natural pulse for ~18 hours you lose the freebie
– On GLP-1s: morning GH is even more important since RETA keeps insulin elevated for days
– Josh's dose: 6 IU before bed, fasted spectacular results

⚗️ Favorite Compounds — Round Table
– Josh: Testosterone cypionate daily (long ester), Masteron E, micro-dose Tren, EQ for aromatizers. Never needed an AI even at 600mg test/week
– JD: Low test base, Winstrol to kick start, Masteron, occasional Primo. AOD, 5-Amino-1MQ, Testofensine, HGH 2 IU
– Will: Sustanon 3x/week, Masteron, Winstrol, Cardarine for athletic performance. HCG 1500 IU + HMG for fertility prep. Low dose RETA twice/week for brain function

🧠 Real talk on gear
– More gear is not always better diminishing returns are real above 800mg test
– Anavar is a starter drug because people are scared Winstrol actually does more
– If you don't know the difference between esters, you're not ready

📺 Subscribe for more no-fluff peptide education every week.

Follow us on social media:
JD's Instagram: https://www.instagram.com/jddenhamofficial/
Will's Instagram: https://www.instagram.com/williamthaas/
Subscribe to our Newsletter: https://potwnewsletter.beehiiv.com/

Follow Josh Holyfield:
Instagram: https://www.instagram.com/josh.holyfield/
YouTube: https://www.youtube.com/@josh_holyfield

Join The Community: https://www.skool.com/peptideoftheweekcommunity

Medical Disclaimer: We are not doctors. The content in this video is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk.

Welcome back, warriors! In this week's Peptide Q&A, JD Denham and William T. Haas cover a teenage son with chronic boils, TRT for weight loss and low energy, MCT vs seed oil carriers, fasting on Retatrutide, fertility protocols for special forces veterans, and what to do when MOTS-C causes a lasting reaction.

Chapters:
 00:00 – Studio Updates & Upcoming Guests
09:15 – Gut Health, Immunity & Healing Protocols
14:09 – TRT, Weight Loss & Low Testosterone
20:03 – Women's Hormones, Energy & ADHD
26:01 – Fat Loss, Libido & TRT Optimization
32:00 – Injection Reactions & MOTS-c Side Effects
34:23 – Gut Inflammation, IBD & Healing Peptides
39:08 – Anxiety, Depression & Brain Peptides
41:36 – TRT, Carrier Oils & Performance
49:42 – Fasting, RETA & Muscle Retention
53:09 – Fertility, TRT & Family Planning

We cover:
• Teenage Son with Chronic Boils & Gut Issues: Why stopping antibiotics, running oral BPC and KPV, and getting a stool test done may matter more than any peptide
• TRT at 45 with 300 Pounds to Lose: Why waiting for weight loss to fix testosterone is swimming upstream and why starting low-dose TRT now changes everything faster
• ER Nurse with ADHD, Celiac & Low Energy: Why Modafinil beats Adderall long term, why Selank and Semax are the right pairing, and why hormones need to be checked first
• Low Energy & Low Libido on Retatrutide + TRT: Why rapid fat loss suppresses natural testosterone, why Kisspeptin doesn't work on TRT, and why HCG is the right call instead
• MOTS-C Allergy — What To Do: Why some people simply can't tolerate it, why SS-31 and NAD cover most of the same ground, and why Paul Bakhtiar has the same reaction
• IBD Protocol for Wife: Why oral and injectable BPC plus KPV are the right tools and how long you can realistically run them
• PSA Concerns on High-Dose TRT: Why DHT management matters, what estrogen symptoms to watch for, and when finasteride or dutasteride may be needed
• Coming Off Anti-Anxiety Meds: Why Selank, Semax, Tesofensine and PE2228 cover anxiety and depression from different angles and why meditation and movement still matter most
• Low Testosterone at 30 in Australia — MCT vs Seed Oil Carriers: Why MCT wins on purity and dispersal, why Proviron enhances TRT naturally, and what to watch for with post-injection pain
• Fasting on Retatrutide: Why Retatrutide actually protects muscle during fasting through insulin signaling and why training fasted accelerates results
• Special Forces Vet Trying for Baby #2: Why HCG, HMG and N-Clomiphene together beat Clomid alone and why TRT during conception is more doable than most doctors admit

📌 Subscribe for weekly, no-fluff protocols, dosing guidance, and real-world results.

You're a warrior. Act like one.

Follow us on social media:
JD's Instagram: https://www.instagram.com/jddenhamofficial/
Will's Instagram: https://www.instagram.com/williamthaas/
Join The Community: https://www.skool.com/peptideresearchinstitute/about
Subscribe to our Newsletter: https://potwnewsletter.beehiiv.com/