Diabetes Care "On Air"

• The art of Diabetes Care, Geremia Bolli on the modern role of basal insulin in advancing T2D therapy, Michael Bowen on the derivation and validation of D-RISK, and more!

  Welcome to episode no. 32 (May 2025) of Diabetes Care “On Air”—a new and different way to bring the research published in Diabetes Care to life. Join co-hosts Alice Cheng, MD, FRCPC, and Michael Rickels, MD, MS, as they discuss the latest and greatest content in the May 2025 issue of Diabetes Care and beyond. 2:30 Alice is joined by John Buse, MD, PhD, endocrinologist and Director of the Diabetes Care Center at the University of North Carolina Chapel Hill (UNC), and Mary Beth Cassely, MSPH, Director of the Innovation Program team at UNC. Husband and wife, they’re also the photographers behind the May issue cover art. Their profile is available for free at doi.org/10.2337/dci25-0026. 14:45 Mike speaks with Geremia B Bolli, MD, an endocrinologist at the University of Perugia, in Italy, and first author of the article, “The Modern Role of Basal Insulin in Advancing Therapy in People With Type 2 Diabetes,” available for free at doi.org/10.2337/dci24-0104. 26:25 Discussing a feature article, “Derivation and Validation of D-RISK: An Electronic Health Record–Driven Risk Score to Detect Undiagnosed Dysglycemia in Clinical Practice,” Alice is joined by lead author Michael E. Bowen, MD. Dr. Bowen is Associate Professor in the Department of Internal Medicine, the Department of Population and Data Sciences, and the Department of Pediatrics at UT Southwestern Medical Center in Dallas, Texas. This article is available for free at doi.org/10.2337/dc24-1624. 52:35 In the “Diabetes Care Rapid Exchange,” Alice and Mike wrap up the episode by reviewing several interesting articles in the May 2025 issue of Diabetes Care. Studies highlighted in this segment include: Rickels et al. Islet Transplantation Versus Standard of Care for Type 1 Diabetes Complicated by Severe Hypoglycemia From the Collaborative Islet Transplant Registry and the T1D Exchange Registry doi.org/10.2337/dc24-1915 Zhao et al. Association Between Use of Sodium–Glucose Cotransporter 2 Inhibitors and Epilepsy: A Population-Based Study Using Target Trial Emulation doi.org/10.2337/dc24-2532 Boonpattharatthiti et al. Comparison of Insulin Titration Strategies for Glycemic Control in Type 2 Diabetes: A Systematic Review and Network Meta-analysis doi.org/10.2337/dc24-2661 Wang et al. Association Between Diabetes and Anemia: Evidence From NHANES and the UK Biobank doi.org/10.2337/dc24-2535 Ostrominski  et al. Efficacy and Safety of Finerenone in Type 2 Diabetes: A Pooled Analysis of Trials of Heart Failure and Chronic Kidney Disease doi.org/10.2337/dc24-1873 Thierry et al. Short-term Metformin Protects Against Glucocorticoid-Induced Toxicity in Healthy Individuals: A Randomized, Double-Blind, Placebo-Controlled Trial doi.org/10.2337/dc24-2039 To learn more about Diabetes Care, please visit diabetesjournals.org/care. Interested in submitting cover art to the journal? Please visit https://diabetesjournals.org/care/pages/submit_a_cover_image.

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• Managing hyperglycemia in the hospital, glycemic impact of protein ingestion in T1D, and more!

  Welcome to episode no. 31 (April 2025) of Diabetes Care “On Air”—a new and different way to bring the research published in Diabetes Care to life. Join co-hosts Alice Cheng, MD, FRCPC, and Michael Rickels, MD, MS, as they discuss the latest and greatest content in the April 2025 issue of Diabetes Care and beyond. Our hosts begin by highlighting some fun facts about April. Of note: it’s Defeat Diabetes Month! This campaign aims to raise awareness around issues of diabetes prevention and management. 2:07 Mike is joined by Linnea M. Wilson, Clinical Research Coordinator at the Beth Israel Deaconess Medical Institution in Boston and Timothy S. Anderson, MD, MAS, Assistant Professor of Medicine at the Center for Research on Health Care at the University of Pittsburgh in Pennsylvania. They discuss their article, “Management of Diabetes and Hyperglycemia in the Hospital: A Systematic Review of Clinical Practice Guidelines,” available for free at doi.org/10.2337/dc24-2510. 15:00 Alice speaks with Dale J. Morrison, PhD, an exercise physiologist and research fellow at the University of Melbourne as part of the Diabetes Technology Research Group. His Perspectives in Care article, “The Glycemic Impact of Protein Ingestion in People With Type 1 Diabetes,” is available for free at doi.org/10.2337/dci24-0096. 38:40 In the “Diabetes Care Rapid Exchange,” Alice and Mike wrap up the episode by reviewing several interesting articles in the April 2025 issue of Diabetes Care. Studies highlighted in this segment include: Cromie et al. Diabetes Risk After Treatment for Childhood and Young Adult Cancer doi.org/10.2337/dc24-2171 Wentworth et al. Islet Autoantibody Screening Throughout Australia Using In-Home Blood Spot Sampling: 2-Year Outcomes of Type1Screen doi.org/10.2337/dc24-2443 Kang et al. Longitudinal Associations of PFAS Exposure With Insulin Sensitivity and β-Cell Function Among Hispanic Women With a History of Gestational Diabetes Mellitus doi.org/10.2337/dc24-2056 Desouter et al. Repeated OGTT Versus Continuous Glucose Monitoring for Predicting Development of Stage 3 Type 1 Diabetes: A Longitudinal Analysis doi.org/10.2337/dc24-2376 Lau et al. Development and Validation of the Patient-Level Chinese Diabetes Outcome Model on Long-term Complications in Type 2 Diabetes: An Application of the Hong Kong Diabetes Register doi.org/10.2337/dca24-0069 Olsen et al. In-Hospital Diabetes Management by a Diabetes Team and Insulin Titration Algorithms Based on Continuous Glucose Monitoring or Point-of-Care Glucose Testing in Patients With Type 2 Diabetes (DIATEC): A Randomized Controlled Trial doi.org/10.2337/dc24-2222 To learn more about Diabetes Care, please visit diabetesjournals.org/care. Interested in submitting cover art to the journal? Please visit https://diabetesjournals.org/care/pages/submit_a_cover_image.

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  44:52
• Financial interventions for diabetes care, glucagon-like peptide 1 receptor agonist outcomes for asian & white populations, and more!

  Welcome to episode no. 30 (March 2025) of Diabetes Care “On Air”—a new and different way to bring the research published in Diabetes Care to life. Join co-hosts Alice Cheng, MD, FRCPC, and Michael Rickels, MD, MS, as they discuss the latest and greatest content in the March 2025 issue of Diabetes Care and beyond. To mark the month of Ramadan, our hosts begin by highlighting a series of practical resources to help people with diabetes minimize risk while religious fasting. These resources include Section 5 of the 2025 Standards of Care, as well as guidelines provided by the Diabetes and Ramadan International Alliance. 2:45 Mike is joined by Leonard E. Egeda, MD, MS, FACP, the Charles and Mary Bauer Professor of Medicine and Chair of the Department of Medicine at the University at Buffalo Jacobs School of Medicine and Biomedical Sciences in Buffalo, New York. They discuss his article, “Financial Incentives, Income Supplementation, Cash Transfer, and Universal Basic Income Interventions in Diabetes: Understanding Differences and Effectiveness: A Scoping Review,” available for free at doi.org/10.2337/dci24-0072. 15:30 Alice speaks with Matthew Lee, PhD, Cardiology Senior Lecture and Honorary Clinical Lecturer at the University of Glasgow, and Naveed Sattar, PhD, Professor of Cardiometabolic Medicine and Honorary Consultant at the University of Glasgow. Their meta-analysis, “Comparative Efficacy of Glucagon-Like Peptide 1 Receptor Agonists for Cardiovascular Outcomes in Asian Versus White Populations: Systematic Review and Meta-analysis of Randomized Trials of Populations With or Without Type 2 Diabetes and/or Overweight or Obesity,” is available for free at https://doi.org/10.2337/dc24-1533. 28:40 In the “Diabetes Care Rapid Exchange,” Alice and Mike wrap up the episode by reviewing several interesting articles in the March 2025 issue of Diabetes Care. Studies highlighted in this segment include: Bardenheier et al. Prevalence of Diagnosed Diabetes Among U.S. Adults Aged ≥18 Years With Disabilities, 2021–2022 doi.org/10.2337/dci24-0086 Xu et al. Incidence and Risk Factors of Diagnosed Young-Adult-Onset Type 2 Diabetes in the U.S.: The National Health Interview Survey 2016–2022 doi.org/10.2337/dc24-1699 Griffin et al. Use of SGLT2i Versus DPP-4i as an Add-on Therapy and the Risk of PAD-Related Surgical Events (Amputation, Stent Placement, or Vascular Surgery): A Cohort Study in Veterans With Diabetes doi.org/10.2337/dc24-1546 Osmulski et al. Subtypes of Gestational Diabetes Mellitus Are Differentially Associated With Newborn and Childhood Metabolic Outcomes doi.org/10.2337/dc24-1735 Hirsch et al. A Randomized Trial Comparing Inhaled Insulin Plus Basal Insulin Versus Usual Care in Adults With Type 1 Diabetes doi.org/10.2337/dc24-1832 Barovic et al. Proteomic and Metabolomic Signatures in Prediabetes Progressing to Diabetes or Reversing to Normoglycemia Within 1 Year doi.org/10.2337/dc24-1412 To learn more about Diabetes Care, please visit diabetesjournals.org/care. Interested in submitting cover art to the journal? Please visit https://diabetesjournals.org/care/pages/submit_a_cover_image.

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  40:51
• Individualized care in dialysis-dependent kidney failure, lessons learned from the epidemiology of T2D in South Asians, and more!

  Welcome to episode no. 29 (February 2025) of Diabetes Care “On Air”—a new and different way to bring the research published in Diabetes Care to life. Join co-hosts Alice Cheng, MD, FRCPC, and Michael Rickels, MD, MS, as they discuss the latest and greatest content in the February 2025 issue of Diabetes Care and beyond. Our hosts return to their usual format, interviewing authors of featured articles before concluding with their Rapid Exchange segment. But first, Alice shares some fun facts of the month and checks in on Mike’s progress with his New Year’s resolution. 2:30 Alice is joined by Klara Klein, MD, PhD, endocrinologist from the University of North Carolina School of Medicine, to discuss her Perspectives in Care article, “Glycemic Management and Individualized Diabetes Care in Dialysis-Dependent Kidney Failure.” This article is available for free at doi.org/10.2337/dci24-0081. 18:55 Mike sits down with Viswanathan Mohan, M.D., Ph.D., D.Sc., FRCP, FNA, FACE, FTWAS, MACP, president and chief of diabetes research at Madras Diabetes Research Foundation, and chairman and chief diabetologist at Dr. Mohan’s Diabetes Specialities Centre in Chennai, India. His article, “Lessons Learned From Epidemiology of Type 2 Diabetes in South Asians: Kelly West Award Lecture 2024,” is available for free at doi.org/10.2337/dci24-0046. 57:30 In the “Diabetes Care Rapid Exchange,” Alice and Mike wrap up the episode by reviewing several interesting articles in the February 2024 issue of Diabetes Care. Studies highlighted in this segment include: Hennekes et al. Diabetes Body Project: Acute Effects of an Eating Disorder Prevention Program for Young Women With Type 1 Diabetes. A Multinational Randomized Controlled Trial doi.org/10.2337/dc24-1599 Laffel et al. Limitations in Achieving Glycemic Targets From CGM Data and Persistence of Severe Hypoglycemia in Adults With Type 1 Diabetes Regardless of Insulin Delivery Method doi.org/10.2337/dc24-1474 Neumiller et al. Compounded GLP-1 and Dual GIP/GLP-1 Receptor Agonists: A Statement from the American Diabetes Association doi.org/10.2337/dci24-0091 Ohkuma et al. Intensive Glucose Lowering and Its Effects on Vascular Events and Death According to Age at Diagnosis and Duration of Diabetes: The ADVANCE Trial doi.org/10.2337/dc24-1516 Flory et al. Large Language Model GPT-4 Compared to Endocrinologist Responses on Initial Choice of Glucose-Lowering Medication Under Conditions of Clinical Uncertainty doi.org/10.2337/dc24-1067 McGrail et al. Genetic Discovery and Risk Prediction for Type 1 Diabetes in Individuals Without High-Risk HLA-DR3/DR4 Haplotypes doi.org/10.2337/dc24-1251 Drzymalla et al. Additive Value of Polygenic Risk Score to Family History for Type 2 Diabetes Prediction: Results From the All of Us Research Database doi.org/10.2337/dc24-1537 To learn more about Diabetes Care, please visit diabetesjournals.org/care. Interested in submitting cover art to the journal? Please visit https://diabetesjournals.org/care/pages/submit_a_cover_image.  

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  1:11:00
• Updates to the 2025 Standards of Care, and more!

  Welcome to episode no. 28 (January 2025) of Diabetes Care “On Air”—a new and different way to bring the research published in Diabetes Care to life. Join co-hosts Alice Cheng, MD, FRCPC, and Michael Rickels, MD, MS, as they discuss the latest and greatest content in the January 2025 issue of Diabetes Care and beyond. In the first episode of the new year, Mike and Alice share their New Year’s resolutions before launching into a special format: celebrating the publication of the acclaimed annual update to the American Diabetes Association’s Standards of Care in Diabetes. 3:00 Our hosts are joined by Rozalina G. McCoy, MD, MS, Director, Precision Medicine and Population Health Program for the University of Maryland Institute for Health Computing and Associate Division Chief for Clinical Research, Division of Endocrinology, Diabetes, and Nutrition. They discuss the Standards of Care 2025 updates and the methodology behind the decision-making process. 31:25 In the “Diabetes Care Rapid Exchange,” Alice and Mike wrap up the episode by reviewing several interesting articles in the January 2025 issue of Diabetes Care. Studies highlighted in this segment include: Mittendorfer et al. Effects of Obesity and Hyperglycemia on Postprandial Insulin-Mediated and Non–Insulin-Mediated Glucose Disposal doi.org/10.2337/dc24-1280 Boeder et al. Combination SGLT2 Inhibitor and Glucagon Receptor Antagonist Therapy in Type 1 Diabetes: A Randomized Clinical Trial doi.org/10.2337/dc24-0212 Sundberg et al. Using Time in Tight Glucose Range as a Health-Promoting Strategy in Preschoolers With Type 1 Diabetes doi.org/10.2337/dci24-0058 Harms et al. Associations of Clinical Characteristics With Sudden Cardiac Arrest in People With Type 2 Diabetes With and Without Cardiovascular Disease: A Longitudinal Case-Control Study Using Routine Primary Care Data doi.org/10.2337/dc24-0715 Chokshi et al. Reduced Aqueous Retinol-Binding Protein 3 Concentration Is Associated With Diabetic Macular Edema and Progression of Diabetic Retinopathy doi.org/10.2337/dc24-1260 Yi et al. Life Course Associations Between Ambient Fine Particulate Matter and the Prevalence of Prediabetes and Diabetes: A Longitudinal Cohort Study in Taiwan and Hong Kong doi.org/10.2337/dc24-1041 To learn more about Diabetes Care, please visit diabetesjournals.org/care. Interested in submitting cover art to the journal? Please visit https://diabetesjournals.org/care/pages/submit_a_cover_image.  

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