217 episodes
Episode 217: AI therapists, theta-bursts for depression, finerenone for CKD, and GLP-1s causing vision loss.
2026-10-07 | 32 mins.This week, Henry, Kate, Gary and Mark talk about 4 great new studies: is using an AI chat therapist really that bad for youth, theta-burst stimulation for adults with major depressive disorder, finerenone in adults with CKD but not DM, and GLP-1 agonists and vision loss risk.Episode 216: low back pain, nasal saline for URI, non-gated CTs for CAC, and statins after 70,
2026-09-22 | 34 mins.Join our intrepid primary care experts Kate Rowland, Mark Ebell, Henry Barry and Gary Ferenchick as they tell you about 4 new primary care relevant studies: self-management and manipulation for low back pain, nasal saline for treating adults with URIs, non-gated CT scans and coronary calcium measurement, and statins after age seventy.
Links:
Low back pain: https://pubmed.ncbi.nlm.nih.gov/42223934/
Nasal saline spray for URI: https://pubmed.ncbi.nlm.nih.gov/41136239/
Recipe for spray: https://www.aaaai.org/tools-for-the-public/conditions-library/allergies/saline-sinus-rinse-recipe
Gated vs non-gated CT: https://pubmed.ncbi.nlm.nih.gov/42507772/
Statins after 70: https://pubmed.ncbi.nlm.nih.gov/42670961/
Permanent link to the John Hickner Scholarship Fund: https://give.msu.edu/?sid=17374Episode 215: self collected HPV, AI skin cancer app, electroacupuncture for neuralgia, and asymptomatic cardiac plaque
2026-09-09 | 35 mins.This week, primary care experts Drs. Kate Rowland, Gary Ferenchick, Mark Ebell and Henry Barry discuss 4 new studies: The post-Papanicolau era of HPV self collection, electroacupuncture for post-herpetic neuralgia, AI-based app for melanoma detection, and the onset age of silent atherosclerosis.
Links:
Self-collected HPV: https://pubmed.ncbi.nlm.nih.gov/42509175/
Electroacupuncture: https://pubmed.ncbi.nlm.nih.gov/42189557/
AI skin cancer app: https://pubmed.ncbi.nlm.nih.gov/41701029/
Silent plaques: https://pubmed.ncbi.nlm.nih.gov/42670946/Episode 214: hyperemesis treatment, Ca++ and Vit D, oral PCSK-9, and semaglutide for dementia (?)
2026-08-27 | 27 mins.Primary care physicians Kate, Mark, Henry and Gary discuss 4 new studies that could change your practice: treatments for hyperemesis gravidarum, calcium and vitamin D to prevent falls and fractures in older adults, the first oral PCSK9 inhibitor, and oral semaglutide to treat dementia .
The John Hickner Memorial fund at MSU: https://give.msu.edu/?sid=17374
Hyperemesis gravidarum treatments: https://pubmed.ncbi.nlm.nih.gov/41478546/
Supplementing with calcium or vitamin D: https://pubmed.ncbi.nlm.nih.gov/42161415/
Oral PCSK-9 enlicitide: https://pubmed.ncbi.nlm.nih.gov/41879224/
Cochrane review of PCSK-9s: https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD011748.pub3/full
Semaglutide for dementia: https://pubmed.ncbi.nlm.nih.gov/41865758/- This week, Kate, Gary and Mark discuss 3 new studies: whether we can do anything about modifiable risk factors for dementia, whether COVID-19 vaccines are still useful, and how to interpret abnormal shoulder MRIs.
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About Primary Care Update
Four healthily skeptical primary care physicians discuss the latest in primary care medicine. Join Essential Evidence Editor Mark Ebell MD, Rush University's Kate Rowland MD, MSU Professor of Medicine Gary Ferenchick MD, and POEMs co-founder Henry Barry MD, MS for this fast-paced weekly update on evidence-based primary care.
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